Serious need dht derivative thats as strong as dht (6 Viewers)

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View attachment 43598View attachment 43599

One study doesn't make your claim true specially when there are hundreds more proving otherwise.

 

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ahmed in the fucking desert has nothing but cactus's and camels to eat that nigga 100% has more dimorphism than the modern western man, u got proof they had 20-33% less test than modern western man?

thats just a stupid stereotype and a claim without any actual scientific evidence or base lol.

 

[atrophicpyra]

One study doesn't make your claim true specially when there are hundreds more proving otherwise.

https://pmc.ncbi.nlm.nih.gov/articles/PMC3120862/

 

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View attachment 43600

https://pmc.ncbi.nlm.nih.gov/articles/PMC3120862/

yea cuz mice studies are def a good reference! 100% same biology

https://pmc.ncbi.nlm.nih.gov/articles/PMC2684818/

https://pubmed.ncbi.nlm.nih.gov/26225793/

this are the updated studies with RCTs and placebo control, both actually found a slight increase in BMD due to higher circulating testosterone.
Dutasteride improved femoral BMD (mean +6%, p<0.01)

 

[atrophicpyra]

One study doesn't make your claim true specially when there are hundreds more proving otherwise.

maybe their area was just not feasible enough for growth who knows u gotta ask the other 100000 other tribes in human history to find a real conclusion

 

[Synapse]

maybe their area was just not feasible enough for growth who knows u gotta ask the other 100000 other tribes in human history to find a real conclusion

 

[atrophicpyra]

yea cuz mice studies are def a good reference! 100% same biology

https://pmc.ncbi.nlm.nih.gov/articles/PMC2684818/
https://pubmed.ncbi.nlm.nih.gov/26225793/
this are the updated studies with RCTs and placebo control, both actually found a slight increase in BMD due to higher circulating testosterone.
Dutasteride improved femoral BMD (mean +6%, p<0.01)

mice and humans have the same bone cells wtf r u on abt they r 100% good enough to study bone anbolic compounds on and to in general test how the human bones work.


.. also wtf r u on they test femur's, facial bones and femurs are NOT the same bone type

long bones probably rely more on estrogen and testosterone because they bare alot of strain however facial bones growth from sutures hence why they grow for a longer period of time than ur femur


plus the study i linked were rats still growing yours was probably fully grown men

 

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mice and humans have the same bone cells wtf r u on abt they r 100% good enough to study bone anbolic compounds on and to in general test how the human bones work.


.. also wtf r u on they test femur's, facial bones and femurs are NOT the same bone type

long bones probably rely more on estrogen and testosterone because they bare alot of strain however facial bones growth from sutures hence why they grow for a longer period of time than ur femur

yeah right, using that logic PTH analogs are 100% the right approach to re open growth plates just bcz mice studies showed that it can re open growth plates on mice, JFL.

 

[atrophicpyra]

yeah right, using that logic PTH analogs are 100% the right approach to re open growth plates just bcz mice studies showed that i can re open growth plates, JFL.

chrondrocyte cells are so different from osteoblastic cells


who knows what if u can, yk what imma try it out in a week

 

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mice and humans have the same bone cells wtf r u on abt they r 100% good enough to study bone anbolic compounds on and to in general test how the human bones work.


.. also wtf r u on they test femur's, facial bones and femurs are NOT the same bone type

long bones probably rely more on estrogen and testosterone because they bare alot of strain however facial bones growth from sutures hence why they grow for a longer period of time than ur femur


plus the study i linked were rats still growing yours was probably fully grown men

thats just not true at all lol

https://pubmed.ncbi.nlm.nih.gov/11956450/

 

[atrophicpyra]

thats just not true at all lol
View attachment 43606

why is there no predict growth chart? what if their zygomatic bones were supposed to be 100% completed by 15 and fully developed? or the opposite?

also u linked same study

 

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why is there no predict growth chart? what if their zygomatic bones were supposed to be 100% completed by 15 and fully developed? or the opposite?

also u linked same study

i did not, and height is mostly linear growth from long bone growth plates, on the other hand facial bones grow in multiple complex directions as they develop frontally, laterally, downward, etc.

 

[atrophicpyra]

i did not, and height is mostly linear growth from long bone growth plates, on the other hand facial bones grow in multiple complex directions as they develop frontally, laterally, downward, etc.

yea for example the mandible is dense in ar, the guy said how it was low in ar5 but thats just not true they 100% haave a good amount of ar5 since all osteoblastic cells have ar5 in them

 

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why is there no predict growth chart? what if their zygomatic bones were supposed to be 100% completed by 15 and fully developed? or the opposite?

also u linked same study

And also u can't standardize a growth pattern for all ethnicities, the 16-18 growth plates closure and fusion is just a rough estimate that is very accurate, same with facial bones and their development, still, the data tracks and the average fusion ages too.

 

[atrophicpyra]

he data tracks and the average fusion ages too.

where?

 

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thats just not true at all lol
View attachment 43606
https://pubmed.ncbi.nlm.nih.gov/11956450/

where?

 

[atrophicpyra]

the link u sent is the finasteride study finasteride is so weak compared to dutasteride

 

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yea cuz mice studies are def a good reference! 100% same biology

https://pmc.ncbi.nlm.nih.gov/articles/PMC2684818/
View attachment 43604
https://pubmed.ncbi.nlm.nih.gov/26225793/
View attachment 43605

this are the updated studies with RCTs and placebo control, both actually found a slight increase in BMD due to higher circulating testosterone.
Dutasteride improved femoral BMD (mean +6%, p<0.01)

where?

https://news.ucsb.edu/2012/013225/l...esponds-competition-according-anthropologists

thats just not true at all lol
View attachment 43606
https://pubmed.ncbi.nlm.nih.gov/11956450/

anyways the dutasteride cope of BMD debunked, the primal bs u said too, the facial bone development as well, keep backpeddling lmfao.

 

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the link u sent is the finasteride study finasteride is so weak compared to dutasteride

https://pubmed.ncbi.nlm.nih.gov/26225793/
ur stupid dut study debunking ur own claims, again.

 

[atrophicpyra]

anyways the dutasteride cope of BMD debunked, the primal bs u said too, the facial bone development as well, keep backpeddling lmfao.

https://pubmed.ncbi.nlm.nih.gov/26225793/

patients with prostate enlargement prob are 45 yr olds not relevant to us, u need studies from ppl who r still in puberty

https://pubmed.ncbi.nlm.nih.gov/26225793/
ur stupid dut study debunking ur own claims, again.
View attachment 43607

 

[atrophicpyra]

anyways the dutasteride cope of BMD debunked, the primal bs u said too, the facial bone development as well, keep backpeddling lmfao.

the tribal shit isnt debunked u just showed one tribe out of thousnads

 

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patients with prostate enlargement prob are 45 yr olds not relevant to us, u need studies from ppl who r still in puberty

used men aged 18, same findings jfl.
https://pmc.ncbi.nlm.nih.gov/articles/PMC2684818/?utm

 

[atrophicpyra]

used men aged 18, same findings jfl.
https://pmc.ncbi.nlm.nih.gov/articles/PMC2684818/?utm

18 when bones are fully developed jfl u need pubertal boys who r 14-16

also rep me or im refunding my reps nigga

 

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18 when bones are fully developed jfl u need pubertal boys who r 14-16

whos telling u to block dht at during those years? and no, they still wont affect it.

 

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18 when bones are fully developed jfl u need pubertal boys who r 14-16

also rep me or im refunding my reps nigga

idgaf u are a retard, just take ment o mtren and go have ur descension lmfao, when that occurs show us ur ascension cuz of dht n sheet.

 

[atrophicpyra]

whos telling u to block dht at during those years? and no, they still wont affect it.

thats what everybody on this forum says lol

 

[atrophicpyra]

idgaf u are a retard, just take ment o mtren and go have ur descension lmfao, when that occurs show us ur ascension cuz of dht n sheet.

mtren wtf oral tren?

 

[Synapse]

thats what everybody on this forum says lol

according to who? most people here are 17+

 

[atrophicpyra]

according to who? most people here are 17+

no i know like 3 who r 15-14 taking roids with a dht inhib

 

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mtren wtf oral tren?

just take ment 5-10mg and have ur brotal dht ascension boyo.

 

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the tribal shit isnt debunked u just showed one tribe out of thousnads

https://pubmed.ncbi.nlm.nih.gov/24203318/
https://pubmed.ncbi.nlm.nih.gov/21745624/
https://doi.org/10.1093/ajcn/71.3.682
https://doi.org/10.1093/ajcn.81.2.341
https://doi.org/10.1371/journal.pone.0040503
https://doi.org/10.1002/1520-6505(2000)9:4<156::AID-EVAN5>3.0.CO;2-7
https://doi.org/10.1002/ajpa.22506
https://doi.org/10.1002/ajhb.22573
https://doi.org/10.1126/science.1207701

lmfao.

 

[atrophicpyra]

https://pubmed.ncbi.nlm.nih.gov/24203318/
https://pubmed.ncbi.nlm.nih.gov/21745624/
https://doi.org/10.1093/ajcn/71.3.682
https://doi.org/10.1093/ajcn.81.2.341
https://doi.org/10.1371/journal.pone.0040503
https://doi.org/10.1002/1520-6505(2000)9:4<156::AID-EVAN5>3.0.CO;2-7
https://doi.org/10.1002/ajpa.22506
https://doi.org/10.1002/ajhb.22573
https://doi.org/10.1126/science.1207701

lmfao.

all staged by the governemnt to promote goyetry i know your a mossad agent

 

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anyways the dutasteride cope of BMD debunked, the primal bs u said too, the facial bone development as well, keep backpeddling lmfao.

https://pubmed.ncbi.nlm.nih.gov/24203318/
https://pubmed.ncbi.nlm.nih.gov/21745624/
https://doi.org/10.1093/ajcn/71.3.682
https://doi.org/10.1093/ajcn.81.2.341
https://doi.org/10.1371/journal.pone.0040503
https://doi.org/10.1002/1520-6505(2000)9:4<156::AID-EVAN5>3.0.CO;2-7
https://doi.org/10.1002/ajpa.22506
https://doi.org/10.1002/ajhb.22573
https://doi.org/10.1126/science.1207701

lmfao.

 

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all staged by the governemnt to promote goyetry i know your a mossad agent

 

[atrophicpyra]

im still keeping dht and blasting 1g test

for dick growth

 

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all staged by the governemnt to promote goyetry i know your a mossad agent

FYI
Aajonus had a fake diploma
Goatis receives state benefits for mental retardation
face Low iq writes his courses with chatgpt, and has recently quitted the " primal diet"
https://looksmax.gg/threads/yall-carnivore-primal-ketocels-are-all-boneless.24820/
Mandy jfl.

 

[atrophicpyra]

FYI
Aajonus had a fake diploma
Goatis receives state benefits for mental retardation
face Low iq writes his courses with chatgpt, and has recently quitted the " primal diet"
https://looksmax.gg/threads/yall-carnivore-primal-ketocels-are-all-boneless.24820/
Mandy jfl.

i
dont
look
up
to
them
NIGGA
FOR THE SECOND TIME I AGREE THEY R RETARDS

if im blasting androgens ill probably use test as a base with tren


for now im worried abt plate closure so i ordered aromasin and im taking 12.5mg a week bec of my shit genetics

 

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i
dont
look
up
to
them
NIGGA
FOR THE SECOND TIME I AGREE THEY R RETARDS

if im blasting androgens ill probably use test as a base with tren


for now im worried abt plate closure so i ordered aromasin and im taking 12.5mg a week bec of my shit genetics

dont expect anything from DHT derivatives for facial bones, just do DIY fillers, check orkas and veridics guide, its on BOTB.

 

[atrophicpyra]

dont expect anything from DHT derivatives for facial bones, just do DIY fillers, check orkas and veridics guide, its on BOTB.

fillers r too temp im getting infraorbital fat graft like ehren and implants never filler


what r ur opinions on ai without aas to prolong plate closure do u think its retarded bec im devoting 2 years into this so i need opinions even tho i researched abt it for weeks before buying

 

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fillers r too temp im getting infraorbital fat graft like ehren and implants never filler


what r ur opinions on ai without aas to prolone plate closure do u think its retarded bec im devoting 2 years into this so i need opinions even tho i researched abt it for weeks before buying

ik i was gonna hear that, just dissolve after 12 months and make sure that the filler is placed on the supraperiosteal bone layer.
Orka Veridic can show their good DIY results and ascension.

 

[atrophicpyra]

ik i was gonna hear that, just dissolve after 12 months and make sure that the filler is placed on the supraperiosteal bone layer.
Orka Veridic can show their good DIY results and ascension.

every 12 months i do filler hmm what the fuck do u mean the bone layer

im not doing filler if i physically feel the needle scraping my bone nigga i though u just do the pinch and 45 degree angle method wtf

 

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every 12 months i do filler hmm what the fuck do u mean the bone layer

im not doing filler if i physically feel the needle scraping my bone nigga i though u just do the pinch and 45 degree angle method wtf

https://looksmax.gg/threads/diy-filler-a-practical-guide.22838/
https://looksmax.gg/threads/instant...de-to-diy-chin-filler-injection-videos.22572/
they know their stuff better, ask them.
Credits to
Orka Veridic.

 

[atrophicpyra]

https://looksmax.gg/threads/diy-filler-a-practical-guide.22838/
https://looksmax.gg/threads/instant...de-to-diy-chin-filler-injection-videos.22572/
they know their stuff better, ask them.
Credits to
Orka Veridic.

ok will check it out ty


u still havent told me ur opinion abt the ai for 2 years

 

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ok will check it out ty


u still havent told me ur opinion abt the ai for 2 years

how old are u again?

 

[atrophicpyra]

how old are u again?

15, igf1 levels r gonna drop after max a year and plates gonna close at around 17 years old

 

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15, igf1 levels r gonna drop after max a year and plates gonna close at around 17 years old

yea, some AIs, pth analogs and fgfr3 might theoretically extend that growth period window, Holy did that and it worked for him, u should ask him about the PTH analogs as i don't have experience with them, but they do come with some sides, tho the hypercalcemia is greatly exaggerated for what i know.

 

[atrophicpyra]

yea, some AIs, pth analogs and fgfr3 might theoretically extend that growth period window, Holy did that and it worked for him, u should ask him about the PTH analogs as i don't have experience with them, but they do come with some sides, tho the hypercalcemia is greatly exaggerated for what i know.

fgfr3 inhibs will turn u into a cod zombie

pths like abalo not worth it, maybe if i get more money, might aswel take hgh its on the way soon, i wont take hgh with ai though bec lower e2 levels means lower igf1 conversion from hgh in the liver

 

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chrondrocyte cells are so different from osteoblastic cells


who knows what if u can, yk what imma try it out in a week

Osteoblastic cells only respond to mechanotransduction from wnt activation amongst other pathways to self regulate BMD, but it's only a self regulatory mechanism that works for bone healing after fractures or injuries, it wont give you bone projection, so it doesn't work for bone smashing or stuff like that.

 

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fgfr3 inhibs will turn u into a cod zombie

pths like abalo not worth it, maybe if i get more money, might aswel take hgh its on the way soon, i wont take hgh with ai though bec lower e2 levels means lower igf1 conversion from hgh in the liver

nah not really, just get the more selective fgfr3 inhibitors, and get abalo.

 

[Dexter]

dht binds to androgen receptors directly in the mandible

yeah, so? receptor binding is irrelevant without ligand availability. the question isn't whether DHT can bind mandibular AR, it is whether DHT is present in sufficient conc. at mandibular osteoblasts to meaningfully participate in receptor occupancy.

there are studies showing it increases cortical thickness and plus its needed to maintain density in skeleton similar to estrogen

the periosteum itself lacks the enzymatic activity that converts T to DHT.

and the studies showing DHT increases cortical thickness are predominantly ex vivo or rodent models using supraphysiological concentrations that bear no relationship to human endogenous physiology.

plus its needed to maintain density in skeleton similar to estrogen

what?

the 5ART2D male in one study had normal T levels, near zero DHT throughout entire life, fully functional androgen receptors.

3/4 patients had completely normal BMD. 4th had osteopenia or whatever, can't remember.

also, the estrogen-bone relationship is mediated via completely different receptors (ER alpha, ER beta) and a different mechanism (anti-resorptive via osteoclast apoptosis). DHT doesn't share this mechanism nigga, why are you comparing them?

if DHT was needed for bone density, a suppression like this would cause bone loss. it didn't.

the skeleton requires T and E for maintenance. T acts directly on osteoblasts via AR and indirectly via aromatization to estradiol.

literally if that was true why is it that when ppl r on dht inhibitors they start lacking bone density

shush.

all osteoblast cells have 5ar

true, but irrelevant.
the real question is: which isoform and at what level?

the Notelovitz review explicitly states that periosteal cells dont have 5AR activity. periosteal apposition is the mechanism by which mandibular widening and angular development takes place. presence of 5AR elsewhere, like trabecular osteoblasts, is irrelevant here.