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Serious Why are Fghr3 inhibitors so hyped? (1 Viewer)

Serious Why are Fghr3 inhibitors so hyped?
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In children with achondroplasia they just add like 1,5-2cm extra from expected anual growth(this refering mainly to voso), so how could they have good ROI in people without the disease (knowing they cost a fuckton).
 
Solution
In children with achondroplasia they just add like 1,5-2cm extra from expected anual growth(this refering mainly to voso), so how could they have good ROI in people without the disease (knowing they cost a fuckton).
cuz new niche smart term people can larp yk
no bhai jaans
fibroblast growth hactor 3 inhibitors add like 6-8cm yearly iirc in achondroplasia patients
like direct ones like tyra or infig not voso
and in mice tyra adds height to healthy wild type mice as well, unlike infig which only did to fgfr3 mutant rats
my idea on this was that inhibition of fgf2 and fgf1 was a net gain with achondroplasia but not with healthy patients
i believe tyra would add height to healthy humans
and also it can be stacked with...

birthdefect

pray to the purple powder
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In children with achondroplasia they just add like 1,5-2cm extra from expected anual growth(this refering mainly to voso), so how could they have good ROI in people without the disease (knowing they cost a fuckton).
cuz new niche smart term people can larp yk
no bhai jaans
fibroblast growth hactor 3 inhibitors add like 6-8cm yearly iirc in achondroplasia patients
like direct ones like tyra or infig not voso
and in mice tyra adds height to healthy wild type mice as well, unlike infig which only did to fgfr3 mutant rats
my idea on this was that inhibition of fgf2 and fgf1 was a net gain with achondroplasia but not with healthy patients
i believe tyra would add height to healthy humans
and also it can be stacked with voso since it increases cgmp in chondrocytes
mark as solution
 
Solution
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no bhai jaans
fibroblast growth hactor 3 inhibitors add like 6-8cm yearly iirc in achondroplasia patients
like direct ones like tyra or infig not voso
and in mice tyra adds height to healthy wild type mice as well, unlike infig which only did to fgfr3 mutant rats
my idea on this was that inhibition of fgf2 and fgf1 was a net gain with achondroplasia but not with healthy patients
i believe tyra would add height to healthy humans
and also it can be stacked with voso since it increases cgmp in chondrocytes
mark as solution
Ty bhai.
So tyra is the only fghr3 inhibitor that would help significantly for healthy humans? Technically you could gain some height with infig but it,s way more unpredictable right?
 

birthdefect

pray to the purple powder
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Ty bhai.
So tyra is the only fghr3 inhibitor that would help significantly for healthy humans? Technically you could gain some height with infig but it,s way more unpredictable right?
in mice it just didnt add anything
i dont believe it would do anything for humans either
maybe itll work as an enhancer for other compounds
 

Holy

ig bro
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no bhai jaans
fibroblast growth hactor 3 inhibitors add like 6-8cm yearly iirc in achondroplasia patients
like direct ones like tyra or infig not voso
and in mice tyra adds height to healthy wild type mice as well, unlike infig which only did to fgfr3 mutant rats
my idea on this was that inhibition of fgf2 and fgf1 was a net gain with achondroplasia but not with healthy patients
i believe tyra would add height to healthy humans
and also it can be stacked with voso since it increases cgmp in chondrocytes
mark as solution
same thought process mirin my tyra and voso coming in
 

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