[hide]

Anyone heard of topical oxytocin for wrinkles?

Oxytocin is the “love hormone,”
but there’s some interesting data on it as an anti-aging skin agent when applied topically, especially combined with microneedling to get it through the skin barrier. Very niche, way outside normal retinol territory.

What the research shows​

Mostly recent human-based studies:

• Reduces wrinkle depth and overall skin aging scores
• Lowers inflammation and oxidative stress in skin
• Reduces fibroblast senescence (older, dysfunctional skin cells)
• Improves skin barrier function and healing
• Higher oxytocin levels correlate with more youthful-looking skin

Microneedling seems key for penetration and results.

Looksmax angle​

Targets fine lines, crow’s feet, forehead wrinkles — smoother, younger-looking skin without fillers. Indirect collagen support + anti-inflammatory effect. Very under the radar maxxing compared to stuff like GHK-CU

Caution​

Experimental. Not FDA-approved for cosmetic use.
Oxytocin sourcing = research chem territory (risk of bunk product).
Microneedling done wrong = irritation / damage.
Systemic absorption is possible but studies report low sides.

Protocol used in studies​

• Topical oxytocin (~10–50 IU/ml, DYOR)
• Microneedling 0.5–1.0 mm for delivery
• Sessions every 2–4 weeks
• 4–6 sessions total

Stacking ideas​

Hyaluronic acid (hydration), retinol (collagen) but don’t overlap days.
Some trials paired with LED/red light for healing.
More users talk about melatonin or IGF-1 topicals.


PERFECT FOR LOVELESS TRUECELLS


Read My New high IQ Threads

Pinealon guide
https://looksmax.gg/threads/pinealon-for-sleep-longevity-botb.16175/
Livagen guide
https://looksmax.gg/threads/livagen-niche-peptide-for-anti-aging-botb.16177/
ET-02 guide
https://looksmax.gg/threads/et-02-a-new-topical-for-hair-regrowth-botb.16209/

And REP them

​

Spoiler: Sources

• Randomized split-face human study (oxytocin + microneedling):
  https://www.researchgate.net/public...andomised_Placebo-Controlled_Split-Face_Study
• Oxytocin reduces fibroblast senescence (PMC):
  https://pmc.ncbi.nlm.nih.gov/articles/PMC8374585/
• Oxytocin and skin barrier / inflammation (MDPI):
  https://www.mdpi.com/2079-9284/12/5/184
• Hormonal anti-aging overview:
  https://studyfinds.org/hormonal-fountain-of-youth-endocrine-science-reverse-wrinkles/
• Clinical commentary on oxytocin & skin aging:
  https://www.dermatologytimes.com/view/clinical-study-points-to-oxytocins-antiaging-benefits
• Additional context:
  https://scitechdaily.com/anti-aging...-a-new-way-to-stop-wrinkles-and-graying-hair/
  https://www.news-medical.net/news/2...w-way-to-treat-wrinkles-and-hair-graying.aspx
  https://ifscc.org/wp-content/uploads/2021/10/Zuo-Jinhui-MGdN-2021-submission.pdf

@Eat My Dust

 

[hide]

 

[livelovelarp]

nice

 

[Mirilow]

Anyone heard of topical oxytocin for wrinkles?

Oxytocin is the “love hormone,”
but there’s some interesting data on it as an anti-aging skin agent when applied topically, especially combined with microneedling to get it through the skin barrier. Very niche, way outside normal retinol territory.

What the research shows​

Mostly recent human-based studies:

• Reduces wrinkle depth and overall skin aging scores
• Lowers inflammation and oxidative stress in skin
• Reduces fibroblast senescence (older, dysfunctional skin cells)
• Improves skin barrier function and healing
• Higher oxytocin levels correlate with more youthful-looking skin

Microneedling seems key for penetration and results.

Looksmax angle​

Targets fine lines, crow’s feet, forehead wrinkles — smoother, younger-looking skin without fillers. Indirect collagen support + anti-inflammatory effect. Very under the radar maxxing compared to stuff like GHK-CU

Caution​

Experimental. Not FDA-approved for cosmetic use.
Oxytocin sourcing = research chem territory (risk of bunk product).
Microneedling done wrong = irritation / damage.
Systemic absorption is possible but studies report low sides.

Protocol used in studies​

• Topical oxytocin (~10–50 IU/ml, DYOR)
• Microneedling 0.5–1.0 mm for delivery
• Sessions every 2–4 weeks
• 4–6 sessions total

Stacking ideas​

Hyaluronic acid (hydration), retinol (collagen) but don’t overlap days.
Some trials paired with LED/red light for healing.
More users talk about melatonin or IGF-1 topicals.


PERFECT FOR LOVELESS TRUECELLS


Read My New high IQ Threads

Pinealon guide
https://looksmax.gg/threads/pinealon-for-sleep-longevity-botb.16175/
Livagen guide
https://looksmax.gg/threads/livagen-niche-peptide-for-anti-aging-botb.16177/
ET-02 guide
https://looksmax.gg/threads/et-02-a-new-topical-for-hair-regrowth-botb.16209/

And REP them

​

Spoiler: Sources

• Randomized split-face human study (oxytocin + microneedling):
  https://www.researchgate.net/public...andomised_Placebo-Controlled_Split-Face_Study
• Oxytocin reduces fibroblast senescence (PMC):
  https://pmc.ncbi.nlm.nih.gov/articles/PMC8374585/
• Oxytocin and skin barrier / inflammation (MDPI):
  https://www.mdpi.com/2079-9284/12/5/184
• Hormonal anti-aging overview:
  https://studyfinds.org/hormonal-fountain-of-youth-endocrine-science-reverse-wrinkles/
• Clinical commentary on oxytocin & skin aging:
  https://www.dermatologytimes.com/view/clinical-study-points-to-oxytocins-antiaging-benefits
• Additional context:
  https://scitechdaily.com/anti-aging...-a-new-way-to-stop-wrinkles-and-graying-hair/
  https://www.news-medical.net/news/2...w-way-to-treat-wrinkles-and-hair-graying.aspx
  https://ifscc.org/wp-content/uploads/2021/10/Zuo-Jinhui-MGdN-2021-submission.pdf

@Eat My Dust

Mirin

 

[Kurdish_slayer]

hopefully ur not a gpt fag

 

[hide]

hopefully ur not a gpt fag

gpt cant make that shi up i used ai to put everything together tho

 

[Kurdish_slayer]

gpt cant make that shi up i used ai to put everything together tho

it works ig

 

[hide]

it works ig

I like the new emotions in Threads tho

 

[Kurdish_slayer]

I like the new emotions in Threads tho

what? havent noticed anything?

 

[hide]

what? havent noticed anything?

 

[hide]

Eat My Dust

 

[Kurdish_slayer]

how in the world did u get those

 

[Cheat]

microneedling is my favourite. anti aging skin hack that never lets me down

without it I wouldn't be able to fuck, literally have girls feeling my face, mirin the glass skin

till death do me part im stabbing needles in my face

 

[hide]

microneedling is my favourite. anti aging skin hack that never lets me down

without it I wouldn't be able to fuck, literally have girls feeling my face, mirin the glass skin

till death do me part im stabbing needles in my face

mirinn hopefuel for skincels like me
month 2 on accutane 60mgs rn

 

[Eat My Dust]

hide Stupid ahhh nigga u microneedling is very good regadless of what product u use + using 0.5-1mm micro needle is pretty big it will cause bleeding.

I highly doubt this is actually usefull, just microneedling with something else like tretinion is 100x better, but company's dont make money off that.

And wth are the chuds on this forum even saying bro there soo grey holy freak

 

[hide]

hide Stupid ahhh nigga u microneedling is very good regadless of what product u use + using 0.5-1mm micro needle is pretty big it will cause bleeding.

I highly doubt this is actually usefull, just microneedling with something else like tretinion is 100x better, but company's dont make money off that.

And wth are the chuds on this forum even saying bro there soo grey holy freak

doubt Means: I dont know
so do your own research lil bro

 

[Circadex]

View attachment 17120

More like

 

[hide]

gpt cant make that shi up i used ai to put everything together tho

More like View attachment 17131

 

[Circadex]

gpt cant make that shi up i used ai to put everything together tho

Hmmmm

 

[hide]

Hmmmm

bro you r on my dih 24/7

 

[Circadex]

bro you r on my dih 24/7

I have my eyes on you

 

[hide]

I have my eyes on youView attachment 17132​

as you can see i only used 3 sentences of ai later to fill up;

So shut up aswaganda cel

 

[Cheat]

hide Stupid ahhh nigga u microneedling is very good regadless of what product u use + using 0.5-1mm micro needle is pretty big it will cause bleeding.

I highly doubt this is actually usefull, just microneedling with something else like tretinion is 100x better, but company's dont make money off that.

And wth are the chuds on this forum even saying bro there soo grey holy freak

i do 1.5mm, doesn't cause bleeding at all, just redness + heat, everyone is different

most people won't see much results from 0.5mm, it's too short even for hair growth, unless you are needling the under eyes and nose area, which then because of thin skin you shouldn't exceed 0.5mm

i get dodgy prescriptions for lidocaine 4% minimum, and go from there, won't need to go higher than 1.5mm though unless your skin is FUCKED

 

[hide]

i do 1.5mm, doesn't cause bleeding at all, just redness + heat, everyone is different

most people won't see much results from 0.5mm, it's too short even for hair growth, unless you are needling the under eyes and nose area, which then because of thin skin you shouldn't exceed 0.5mm

i get dodgy prescriptions for lidocaine 4% minimum, and go from there, won't need to go higher than 1.5mm though unless your skin is FUCKED

Why do you microneedel? against scars?

 

[Circadex]

as you can see i only used 3 sentences of ai later to fill up;

View attachment 17133


So shut up aswaganda cel

You know aswaganda is for the hydrocortisone right? because it increases cortisol mildly when starting treatment, and im ASD asf so it's crucial i address it.