When it comes to hair loss, we have the topical and oral (dutasteride, finasteride) options.If you are still going through puberty, the oral options are out of the question, as it can messes with your puberty by lowering or even almost fully eliminating your DHT (the main reason for your shedding).the results of a low DHT during puberty are a slightly slower and less deep voice development, reduced penile growth, reduced prostate growth, and less jaw and face masculinization signals.
So what are the topical options to prevent the norwood reaper from knocking on our door, or at least delay it until our puberty is over?
KX-826 and RU58841 (the only topical options):
How do they work?
Both compounds attach to the AR in your scalp follicles, blocking DHT from binding and both are NSAAs (non‑steroidal and anti-androgens).without DHT, your hair follicles won’t shrink and remain thick, long, and in an overall growth phase (anagen).due to their topical application, they act directly where the problem occurs and minimize the hormone disruption elsewhere in the body, but they do not act as strongly and definitively as their oral substitutes.
KX-826 vs RU58841
RU58841 is primarily used experimentally.it binds to androgen receptors in scalp follicles, partially blocking DHT from triggering follicle miniaturization and hair thinning but will most likely allow some of the DHT activity in your follicles, it also can allow some regrowth sometimes but its binding strength is weaker than KX-826 so you might need to use it more frequently.
On the other hand KX-826 is a newer topical AR antagonist and still primarily used in experiments, same as RU58841 but still newer.the binding strength is higher and more selective than RU58841.due to its binding power it can fully occupy the receptors even when your DHT levels are high, causing an stronger prevention of follicle shrinkage.it could even theoretically reverse early stage miniaturized follicles(individual hair follicles that have started to shrink because of DHT), due to follicles still being alive and potentially allowing them to recover.it also could maintain or even restore your anagen phase length.
None of them are approved yet and still being researched, but KX-826 researches have stopped due to some stupid legal reasons, you can still find them both but RU58841 is more accessible to buy and even cheaper.
(yes i asked jewpt to make me a picture)
bottom line
Oral options are always better but retarded to use during puberty, if you are experiencing hairloss and have to use the topical options you now know the pros and cons of each.but you'd have to keep in mind that both are experimental.if i had to use one which i thankfully dont, i'd use KX-826 if i could find it but if you cant, RU58841 is still fine.
Wishing all of you good luck and a life without hairloss.
So what are the topical options to prevent the norwood reaper from knocking on our door, or at least delay it until our puberty is over?
KX-826 and RU58841 (the only topical options):
How do they work?
Both compounds attach to the AR in your scalp follicles, blocking DHT from binding and both are NSAAs (non‑steroidal and anti-androgens).without DHT, your hair follicles won’t shrink and remain thick, long, and in an overall growth phase (anagen).due to their topical application, they act directly where the problem occurs and minimize the hormone disruption elsewhere in the body, but they do not act as strongly and definitively as their oral substitutes.
KX-826 vs RU58841
RU58841 is primarily used experimentally.it binds to androgen receptors in scalp follicles, partially blocking DHT from triggering follicle miniaturization and hair thinning but will most likely allow some of the DHT activity in your follicles, it also can allow some regrowth sometimes but its binding strength is weaker than KX-826 so you might need to use it more frequently.
On the other hand KX-826 is a newer topical AR antagonist and still primarily used in experiments, same as RU58841 but still newer.the binding strength is higher and more selective than RU58841.due to its binding power it can fully occupy the receptors even when your DHT levels are high, causing an stronger prevention of follicle shrinkage.it could even theoretically reverse early stage miniaturized follicles(individual hair follicles that have started to shrink because of DHT), due to follicles still being alive and potentially allowing them to recover.it also could maintain or even restore your anagen phase length.
None of them are approved yet and still being researched, but KX-826 researches have stopped due to some stupid legal reasons, you can still find them both but RU58841 is more accessible to buy and even cheaper.
(yes i asked jewpt to make me a picture)
bottom line
Oral options are always better but retarded to use during puberty, if you are experiencing hairloss and have to use the topical options you now know the pros and cons of each.but you'd have to keep in mind that both are experimental.if i had to use one which i thankfully dont, i'd use KX-826 if i could find it but if you cant, RU58841 is still fine.
Wishing all of you good luck and a life without hairloss.
