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Guide thougths on my antiaging protocol? (5 Viewers)

Guide thougths on my antiaging protocol?

Synapzyzz

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Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
 

Circadex

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what the fuck???
He probably meant mcg

Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
Just pin KLOW instead, makes it simpler. However, it seems decent. And for epi, isn't it 20 days x2 a year?
Also, isotretinoin should probably be 10mg, just because that's around the dosage they used in the collagen article.
 

Synapzyzz

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He probably meant mcg


Just pin KLOW instead, makes it simpler. However, it seems decent. And for epi, isn't it 20 days x2 a year?
Also, isotretinoin should probably be 10mg, just because that's around the dosage they used in the collagen article.
i did meant mcg, my dumbass didn't realize, chose 5 cause i think its safer for very long term use, but you are probably right, yes, fucked on epi too, i meant 20 days x2 a year.
:headpalm:
 

Ricespice

Typical LTN
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Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
Very similar to what k-pop idols do (no cringe) actua age is 30 but look 18
 

birthdefect

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Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
take klow instead of taking its individual ingredients like the other guy said, and consider adding rapamycin and 17a estradiol
might be able to get away with lowering dutasteride a little bit since 17a estradiol acts as a weak 5ari
 

Michael b

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Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
Vitamin c serums are toxic and ghkcu is extremely dangerous it can cause copper toxicity and hormonal imbalance.
 

Bite

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Jan 19, 2026
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Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
Too much/Upp the isotretinoin to 10mg
 

Bite

Iron
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Jan 19, 2026
Posts
109
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116
Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
Also retinol beats accutane for anti aging since it does more with your collagen
 

Circadex

The real "child of renaissance"
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Iso is more expensive + more side effects especially when you dont have hormonal acne why take it i get your and Ops point tho with taking low doses
10mg and there's no risk. And who cares about cost, if you can't afford 10mg you're subhuman & it's over
 

Endo

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Isotretinoin 5 mg
GHK-CU saline reconstituted 1-3mg daily (until desired effect is achieved, the should lower the dosage to maintenance doses) (4-12 weeks on 5 days off)
KPV 500 mcg (cycle 4–12 weeks) 2-4 off
Epitalon 5–10 mg daily (10–20 day cycle and then cycle again)
BPC 157 500 mg daily TB500 500 mg daily (4–6 weeks on, 2–4 off)
Tazarotene 0.1 during weekends
microneedling once every 5 weeks
Dutasteride 1-2 mg
MSM 1000 mg cycle 8–12 weeks and 1-2 off
pantothenic acid 1000mg
Sunscreen PAA++
NAD+ 1000mg
FOXO4-DRI 100–500 mcg daily 1-3x times a year for 30 days
Vitamin C serum at morning
Or just avoid carbs and sugar and use retinol/retinal/tret
 

birthdefect

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Oral vs topical-faggery; iso mogs
hes right, isotret shrinks sebaceous glands while tret is more focused on increasing skin cell turnover rate
you dont want to nuke sebaceous glands for anti aging either, so tret is likely better for this
all you would really need in an anti aging stack assuming you dont have acne is rapamycin, epitalon, 17a estradiol, tret, and maybe fin or dut
isotret only if you have extremely oily skin that makes it past tret. vitamin c if you really want but i think its unnecessary, and supplementation is completely unnecessary unless you have a deficiency
 

Circadex

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hes right, isotret shrinks sebaceous glands while tret is more focused on increasing skin cell turnover rate
you dont want to nuke sebaceous glands for anti aging either, so tret is likely better for this
all you would really need in an anti aging stack assuming you dont have acne is rapamycin, epitalon, 17a estradiol, tret, and maybe fin or dut
isotret only if you have extremely oily skin that makes it past tret. vitamin c if you really want but i think its unnecessary, and supplementation is completely unnecessary unless you have a deficiency
I was shit posting. But isotret is still more convenient
 

birthdefect

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I was shit posting. But isotret is still more convenient
i mean considering the amount of stuff the dude was planning on (and the fact that much of it was redundant anyways since klow exists) i dont think he cares much about convenience
still tho my little list there mogs literally every anti aging stack in existence since no one seems to use 17a estradiol, only place ive seen it mentioned was some yt video from loox :cage:
 

Circadex

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i mean considering the amount of stuff the dude was planning on (and the fact that much of it was redundant anyways since klow exists) i dont think he cares much about convenience
still tho my little list there mogs literally every anti aging stack in existence since no one seems to use 17a estradiol, only place ive seen it mentioned was some yt video from loox :cage:
Clavicular recommended estradiol cream, no?
But yeah i agree, you listed some goodies.
 

birthdefect

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Clavicular recommended estradiol cream, no?
But yeah i agree, you listed some goodies.
not estradiol cream (although it is good for certain cases)
17a estradiol is a non feminising androgen that increases lifespan (only in males) significantly
its non feminising because its around 100x weaker than the normal estradiol we're used to 17b estradiol
if you're a dude its a compound that has no reason to not be used, also acts as a weak 5ari
 

Circadex

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not estradiol cream (although it is good for certain cases)
17a estradiol is a non feminising androgen that increases lifespan (only in males) significantly
its non feminising because its around 100x weaker than the normal estradiol we're used to 17b estradiol
if you're a dude its a compound that has no reason to not be used, also acts as a weak 5ari
PSL autist vs certified endocrinologist. Who wins?
 

Circadex

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idk whos who here tbh :banderas:
im hoping to actually go into endocrinology or biochem/pharmacology after high school, genuinely find this shit so interesting
I can't imagine you'd have a hard time getting into the profession
 

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