Looksmax The miracle drug for heightmaxing(take it before its too late) (7 Viewers)

Spoiler: Introduction

SAG or the full name smoothened agonist. It is a small molecule that binds directly to the Smoothened (SMO) receptor, which in turn activates Hedgehog signaling.

Spoiler: The mechanism behind it

The Hedgehog pathway is a cellular signaling system that plays a key role in embryonic development, tissue repair, and stem cell maintenance. It operates through a series of molecular interactions, including the binding of Hedgehog proteins to a cellular receptor, which ultimately regulates the expression of genes associated with growth and differentiation.The Hh pathway interacts extensively and context-dependently with the Wnt/β-catenin, BMP, TGF-β, FGF, and PTHrP signaling cascades to form a highly integrated regulatory network required for skeletal formation and morphogenesis.

There is a study where SAG increased the number of stem cells in growth zones, and in another it increased the growth of ad by an insane amount of centimeters.


“Hedgehog pathways via SAG expand the pool of epiphyseal skeletal stem cells (epSSCs) in the growth plate quiescent zone.”


“The study showed an increase relative to vehicle in Ihh-deficient mice: body length +18.9%, vertebral length +32.1%, femur length +67.4%, tibia length +33.1%”

Spoiler: Conclusion

From all that has been said, we can conclude that SAG is a miracle drug that increases growth to the point of madness (even with closed growth plates)


SAG stimulates Hedgehog signaling in growth plates, allowing for increased growth plate length and bone length growth.


Also, considering that SAG costs pennies (if you know where to buy it), we can definitely conclude that this is one of the best drugs for growth in general.


Dose 50 mcg per growth zone daily

Spoiler: Sources

PUBMED12391318


PMC8591400


PMC11063894

Thanks for reading bhais












Special thanks to youngman

 

[fent]

dnr but cancer causing

 

[HailSanta]

dnr but cancer causing

Muh cancer

 

[fent]

Muh cancer

Go ahead take it and doccument

 

[HailSanta]

Go ahead take it and doccument

I will

 

[fent]

I will

be sure to @ me!

 

[dookiebootybutt59]

someone back this up for me

 

[GunnerW]

insane cancer risk and zero studies on humans

 

[Dexter]

cope

if i have time, i will disprove this completely

 

[Hauptmann]

Santa, can you give this to me please?

 

[youngman]

dnr but u tagged me for some reason, ur getting 50 reps tmr cuz this jewish website only allows 50 a day as if were kids