Biomaxx
Qui servat inopes
- Joined
- Oct 12, 2025
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I think ive came across a god made compound that I probably shoudnt be writing about
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SRX-9147 (Soteraxifin): First-In-Class Osteo-Anabolic Mitogen
soreraxfin has just had its first published animal trail (rats)
Soteraxifin was administered 100mcg/kg to teenage rats and showed (imo) incredible results
Results showed- insane femur thickening and lengthening, large increase in bmd, near complete halt in chondrocytes differentiation (plate fusure) and slight myostatin inhibition (more lean muscle)
This compound was seen to work through 4 different main pathway
1.FGFR3 Pathway Inhibition
Unlike expensive antibody approaches, Soteraxfin is a small molecule FGFR3 inhibitor that penetrates the growth plate. Reduces constitutive STAT1 phosphorylation, allowing chondrocytes to stay proliferative longer. No impact on FGFR1/2/4 at therapeutic doses.
2. Wnt/β-Catenin Potentiation
Standard Wnt agonists hit LRP5/6 and wreck your gut. Soteraxfin amplifies endogenous Wnt signaling downstream at the Dvl/Axin level. Result: significant BMD accretion without the GI sides that killed other candidates in this class.
3. Myostatin Latency Maintenance
Binds the myostatin pro-domain with high affinity, preventing proteolytic activation. Serum active myostatin dropped 94% in the 100mcg cohort. Lean mass up 4.2kg in 8 weeks without training protocol changes.
4. CNP/NPR-B Signaling Amplification
Positive allosteric modulator at the NPR-B receptor. Endogenous CNP stays active 3-4x longer in growth plate tissue. cGMP elevation localized to bone - no systemic hypotension or vascular effects seen.
Results over a month-
These results are Unlike anything tested
Side Effects
Reportedly near to none
Mild headaches and early usage stool softening



OPEN SPOILER
soreraxfin has just had its first published animal trail (rats)
Soteraxifin was administered 100mcg/kg to teenage rats and showed (imo) incredible results
Results showed- insane femur thickening and lengthening, large increase in bmd, near complete halt in chondrocytes differentiation (plate fusure) and slight myostatin inhibition (more lean muscle)
This compound was seen to work through 4 different main pathway
1.FGFR3 Pathway Inhibition
Unlike expensive antibody approaches, Soteraxfin is a small molecule FGFR3 inhibitor that penetrates the growth plate. Reduces constitutive STAT1 phosphorylation, allowing chondrocytes to stay proliferative longer. No impact on FGFR1/2/4 at therapeutic doses.
2. Wnt/β-Catenin Potentiation
Standard Wnt agonists hit LRP5/6 and wreck your gut. Soteraxfin amplifies endogenous Wnt signaling downstream at the Dvl/Axin level. Result: significant BMD accretion without the GI sides that killed other candidates in this class.
3. Myostatin Latency Maintenance
Binds the myostatin pro-domain with high affinity, preventing proteolytic activation. Serum active myostatin dropped 94% in the 100mcg cohort. Lean mass up 4.2kg in 8 weeks without training protocol changes.
4. CNP/NPR-B Signaling Amplification
Positive allosteric modulator at the NPR-B receptor. Endogenous CNP stays active 3-4x longer in growth plate tissue. cGMP elevation localized to bone - no systemic hypotension or vascular effects seen.
Results over a month-
These results are Unlike anything tested
Side Effects
Reportedly near to none
Mild headaches and early usage stool softening



OPEN SPOILERApril fools, silly mf 

so bored

