tbh it all depends on person to person for using an Ai with 300mg test, some people are fine with 700mg+ weekly.Don’t need an ai at 300mg test
Saying rad140 is a partial agonist even tho that’s why it’s a sarm, because it’s selective to bone and muscle ar
Saying ur using test for estrogen amplification as if ur letting ur e2 rise high enough for that amplification
JFLLL
that's not what partial agonism means stupid fag, that's what selectivity means.Don’t need an ai at 300mg test
Saying rad140 is a partial agonist even tho that’s why it’s a sarm, because it’s selective to bone and muscle ar
Saying ur using test for estrogen amplification as if ur letting ur e2 rise high enough for that amplification
JFLLL
Dht doesn’t grow bones as far as we know we r both wrong though btw
Why do u think sarms r selective
my clan is called SLYR, wanna join?anyone tryna let me join their clan to look cool
High iq required to know that dht grows bones
yesss that shit tuff
Why do u think sarms r selective
hence the word "partial" agonism jfl he's retarded
Dude it’s a partial agonist to certain tissues
I fully support ur 300mg test e no ai if u let me touch ur boobies after
Dnr
Conclusion they r partial agonist to certain tissues full to others
Reread what I said bro I cant type rn
Reread what I said
can tell you've never taken a chemistry class in your life, selectivity is not even exclusive to a biochemical process fractional distillation of petroleum is still a fucking selective process, same as when you are doing a halogenation of alkenes.
Ok so what does this mean?
partial agonist to the AR receptor nigger, it has a different binding replacing the functional groups of a normal AAS like test.Dude it’s a partial agonist to certain tissues
Gng noo it’s too complicated I don’t even wanna argue abt it just search it up somewhere for a good 30 minutes you’ll know what u mean
yes nigger, receptors have geometric shapes, again, ik you've never taken 1 chemistry class in your life cause you would know this.Ok so what does this mean?
Due to its shape its partial to other full to others hence why it’s selective
That’s what I have been saying they r selective and partial agonists to others full to others
Btw what’s the point in arguing abt this jfl we all know it’s stronger than test that’s no debate
Ok so they r selective because they partially bind to certain receptors whilst bind a lot more to certain tissues like bone and muscle
Testosterone is a full AR agonist, the muscular transcription factor of SARMs are dogshit, they also miss all the anabolism pathways needed to be superior to AAS, also, anabolism is a full system, it does not depend solely on the AR receptor, it has multiple co factors that work in synergy.
Thats just not fucking true, they are related concepts but they are not the same
They have anticatabolic effects similar to tren and transcription of sarms r once again DOGSHIT TO CERTAIN TISSUES but for the selective ones like muscle and bone they r so goated
it’s hard for selective ar activation so the only way u can basically get that is partial androgeny in certain tissues and full in others
hence why they still cause baldness and other efffects
so the whole premise of SARMs is a fucking failure basically jfl
yeah, "similar"
, tren mogs SARMs when it comes to that to oblivion.
Bro who gaf abt that that’s not the reason why ppl use sarms now adaysso the whole premise of SARMs is a fucking failure basically jfl
the whole idea was to get rid of the androgenic sides.
SARMs do fucking nothing for the bones btw.
Yk Anavar tren and sarms r all anti catabolic right?yeah, "similar"
what does anavar has anything to do? yes they all affect the GR receptor in tissues.
Yeah but they do smth for muscle make that make sense jfl
That a lot of things r as catabolic as tren
Yeah but they do smth for muscle make that make sense jfl
They said it’s targeted towards bone and muscle too btw
jesus fucking christ, comparing SARMs and anavar to the anticatabolic effects of tren is insanely retarded
surgerymax, you're the nigga that knows more about tren, are SARM's and anavar as catabolic....oh! nooooo
Jfl that’s ostarine r we deadass
They all produce similar anticatabolic effects wtf r u on abt bro reassessjesus fucking christ, comparing SARMs and anavar to the anticatabolic effects of tren is insanely retarded
Jfl that’s ostarine r we deadass
similar does not mean equal in potency, how illiterate are you?
Weaker ones don’t do much but btw just as a reference if something increases muscle mass it increases bone mass since they r both identical in ar
wtf I said similar not equal? Similar as in similar potency
If that was true BMD would've increased, muscle increased by 1.2 kg, BMD and bones remained the same.
Make that make sense how would that even be possibleIf that was true BMD would've increased, muscle increased by 1.2 kg, BMD and bones remained the same.
"just treat AR receptors in bones and muscle the same, as they are identical in nature, both structures should work the same"" just as a reference if something increases muscle mass it increases bone mass since they r both identical in ar"
