So I’m back to drop some simple information,this isn’t really a guide.
Acidosis:
A state where the blood’s PH drops below 7.35~.
The bicarbonate system regulates your blood’s PH mostly,your average blood PH is between 7.35-7.45.
CO2+H2O<−>H2CO3<−>H++HCO3−
The bicarbonate system regulates further H+,HCO3- (kidneys),CO2 (lungs). If H+ rises then so does the blood PH lower.
In all meat diets, Sulfur precursing compounds are high for example methionine.
Sulfur amino acids (high amounts)->excessive sulfuric acid (H2SO4) -> increase in net acid production -> kidneys excrete more acid= PRAL.
PRAL simply stands for Potenial Renal Acid Load.
Ketones contribute:
Ketone bodies such as acetoacectate, ẞ-hydroxybutyrate that are produces by the liver are mildly acidic,alone they don’t create a acidic effect by itself but paired with excess sulfuric acid can contribute.
Calcium to Phosphorus ratio:
Majority meat diets tend to have a shitty calcium-phosphorus ratio.
Ca-P ratio of meat: 1:20
The calcium to phosphorus ratio is important for your bones because:
Ca2++PO43− −>Ca3(PO4)2, hydroxyapatite
hydroxyapatite is important simply because it’s the mineral base of bone.
You might also ask: “Mandy,outside the skeletal system,does it have any endocrine effects?”
Therefore I answer yes,it does. Now we’re going to look at FGF-23, high phosphorus intake stimulates this endrocrine pathway chronically,therefore:
-Vitamin D (calcitriol) decreases-> downstream endocrine effects. (Too lazy to name all of them)
Ketones+acid load+phosphorus: kidneys work extra to excrete more acid. (Too lazy to write more here)
Your blood PH dosen’t change because your kidneys already do the work,but these change:
-Renal acid secretion
-Net acid production
https://pubmed.ncbi.nlm.nih.gov/29063994/
(Acid)
https://pubmed.ncbi.nlm.nih.gov/25496564/
(Ca:P)
https://pubmed.ncbi.nlm.nih.gov/12716680/
(PRAL)
https://pubmed.ncbi.nlm.nih.gov/38189228/
(FGF-23)
Thank you if you read it all,I hope some of y’all learned something new. Just to say,it’s more about the downstream effects of these things rather than the main starter.
Now I have to wait for the bigger fish to show up for impending rape of all this info and the thread.
Acidosis:
A state where the blood’s PH drops below 7.35~.
The bicarbonate system regulates your blood’s PH mostly,your average blood PH is between 7.35-7.45.
CO2+H2O<−>H2CO3<−>H++HCO3−
The bicarbonate system regulates further H+,HCO3- (kidneys),CO2 (lungs). If H+ rises then so does the blood PH lower.
In all meat diets, Sulfur precursing compounds are high for example methionine.
Sulfur amino acids (high amounts)->excessive sulfuric acid (H2SO4) -> increase in net acid production -> kidneys excrete more acid= PRAL.
PRAL simply stands for Potenial Renal Acid Load.
Ketones contribute:
Ketone bodies such as acetoacectate, ẞ-hydroxybutyrate that are produces by the liver are mildly acidic,alone they don’t create a acidic effect by itself but paired with excess sulfuric acid can contribute.
Calcium to Phosphorus ratio:
Majority meat diets tend to have a shitty calcium-phosphorus ratio.
Ca-P ratio of meat: 1:20
The calcium to phosphorus ratio is important for your bones because:
Ca2++PO43− −>Ca3(PO4)2, hydroxyapatite
hydroxyapatite is important simply because it’s the mineral base of bone.
You might also ask: “Mandy,outside the skeletal system,does it have any endocrine effects?”
Therefore I answer yes,it does. Now we’re going to look at FGF-23, high phosphorus intake stimulates this endrocrine pathway chronically,therefore:
-Vitamin D (calcitriol) decreases-> downstream endocrine effects. (Too lazy to name all of them)
Ketones+acid load+phosphorus: kidneys work extra to excrete more acid. (Too lazy to write more here)
Your blood PH dosen’t change because your kidneys already do the work,but these change:
-Renal acid secretion
-Net acid production
https://pubmed.ncbi.nlm.nih.gov/29063994/
(Acid)
https://pubmed.ncbi.nlm.nih.gov/25496564/
(Ca:P)
https://pubmed.ncbi.nlm.nih.gov/12716680/
(PRAL)
https://pubmed.ncbi.nlm.nih.gov/38189228/
(FGF-23)
Thank you if you read it all,I hope some of y’all learned something new. Just to say,it’s more about the downstream effects of these things rather than the main starter.
Now I have to wait for the bigger fish to show up for impending rape of all this info and the thread.
