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How does HGH actually work?
Human growth hormone, also known as HGH is an endogenously produced peptide hormone that stimulates growth.
HGH converts to insulin like growth factor,also known as IGF1, in the liver.
The anabolic effect of HGH and IGF1
is manifested by the stimulation of bone proliferation, where linear bone growth is promoted by the activation of epiphyseal precondrocytes. IGF1 increases the uptake of amino acids from the bloodstream, enhances cellular proliferation, and has direct anabolic effect on bone mass.
The IGF1 signaling pathway works by turning on gene factors
such as AKT, Erk's and mtor complex one. These are the main drivers of growth leading to increased cranial facial development and even height.
According to clinical research.
HGH replacement therapy has been heavily utilized in combination with aromatase inhibitors to reverse idiopathic short stature in children.
In some conclusion
exogenous HGH injections could actually increase final adult height (with extra pharma) as well as forward projection of cranial facial bones.
Human growth hormone, also known as HGH is an endogenously produced peptide hormone that stimulates growth.
HGH converts to insulin like growth factor,also known as IGF1, in the liver.
The anabolic effect of HGH and IGF1
is manifested by the stimulation of bone proliferation, where linear bone growth is promoted by the activation of epiphyseal precondrocytes. IGF1 increases the uptake of amino acids from the bloodstream, enhances cellular proliferation, and has direct anabolic effect on bone mass.
The IGF1 signaling pathway works by turning on gene factors
such as AKT, Erk's and mtor complex one. These are the main drivers of growth leading to increased cranial facial development and even height.
According to clinical research.
HGH replacement therapy has been heavily utilized in combination with aromatase inhibitors to reverse idiopathic short stature in children.
In some conclusion
exogenous HGH injections could actually increase final adult height (with extra pharma) as well as forward projection of cranial facial bones.



