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Cross post from org for my DIY filler guide I'm releasing tonight, stay tuned for orka's in depth thread.
What is Hyaluronidase?
Hyaluronidase is an enzyme commonly used within the field of aesthetics to "dissolve" hyaluronic acid filler, and reverse any botches/migration when injecting this solution. This functions by spreading locally and breaking down unwanted filler gel tissue.
note: this thread is for educational purposes, what you choose to do with this information is at your own risk.
What is Hyaluronidase?
Hyaluronidase is an enzyme commonly used within the field of aesthetics to "dissolve" hyaluronic acid filler, and reverse any botches/migration when injecting this solution. This functions by spreading locally and breaking down unwanted filler gel tissue.
note: this thread is for educational purposes, what you choose to do with this information is at your own risk.
Supplies
(dm for sourcing)
- Hyaluronidase (usually comes in 1500iu vials)
- Sterile saline for reconstitution
- Insulin syringe (29-31g is standard)
- Alcohol prep pads and gloves
- Lidocaine if preferred (numbing agent)
Prep and Administration
Mixing:
1. Reconstitute your hyaluronidase powder, and add 2-3ml of sterile saline into the vial.
2. Draw solution into your syringe.
Dissolving:
1. Disinfect injection sites and nearby skin tissue before beginning
2. Mark your area of unwanted filler results by tracing around the perimeter
3. Inject small amounts directly into the gel pockets, keep it subdermal and not too deep into muscle tissue (10-30 units per 0.1ml of filler)
4. Massage gently after injection is complete to encourage the solution to spread
- Swelling and inflammation afterwards is normal, any burning sensations typically dissipate after a few hours.
- Avoid blood thinners or alcohol 1-2 days prior to injecting.
- Older filler may require several sessions but no more than 2-3 per site. (Higher risk of natural tissue damage)





