Why choose injection
- Injection is the most common and effective delivery method for peptides. It bypasses the digestive tract, allowing the compound to enter systemic circulation without being broken down by stomach acid or digestive enzymes.
- SubQ injections deposit the peptide into the fatty tissue beneath the skin, where it’s slowly absorbed into the bloodstream. This method is ideal for peptides that require sustained release over time.
Benefits of SubQ Delivery:
- Slower absorption, providing longer-lasting effects
- Ideal for daily or multiday peptides (eg CJC-1295 with DAC)
- Lower injection pain and easier self-administration
why not to choose oral
Oral delivery is the most convenient route for medications, but for peptides, it’s also the most problematic. That’s because peptides are fragile molecules that are easily degraded by stomach acid, digestive enzymes, and the gut’s harsh pH environment before they can reach systemic circulation.
“The oral bioavailability of unmodified peptides is typically less than 1% due to proteolytic degradation and poor epithelial permeability.”
essentially meaning When you swallow most peptides, your stomach destroys them and almost none of it gets into your body — usually less than 1%.
Conclusion
- injectable delivery remains the most effective and reliable method for peptide absorption, especially for performance, recovery, and hormone optimization.
- Subcutaneous or SubQ injections are preferred for long-acting peptides like CJC-1295 with DAC, IGF-1 LR3, and BPC-157.
- Oral peptides face major challenges with digestion and absorption, but breakthroughs like oral semaglutide and permeation enhancers are making GI delivery more viable.
- Nanoparticle delivery systems and other advanced technologies (eg micro needles (only really viable for cosmetic peptides) hydrogels, transdermal patches) are rapidly emerging as non-invasive, next-generation options.
- Your choice of delivery method should match your peptide’s half-life, intended effect, comfort level, and compliance needs.
Overall inject and don't be a fucking bitch about it
- Injection is the most common and effective delivery method for peptides. It bypasses the digestive tract, allowing the compound to enter systemic circulation without being broken down by stomach acid or digestive enzymes.
- SubQ injections deposit the peptide into the fatty tissue beneath the skin, where it’s slowly absorbed into the bloodstream. This method is ideal for peptides that require sustained release over time.
Benefits of SubQ Delivery:
- Slower absorption, providing longer-lasting effects
- Ideal for daily or multiday peptides (eg CJC-1295 with DAC)
- Lower injection pain and easier self-administration
why not to choose oral
Oral delivery is the most convenient route for medications, but for peptides, it’s also the most problematic. That’s because peptides are fragile molecules that are easily degraded by stomach acid, digestive enzymes, and the gut’s harsh pH environment before they can reach systemic circulation.
“The oral bioavailability of unmodified peptides is typically less than 1% due to proteolytic degradation and poor epithelial permeability.”
essentially meaning When you swallow most peptides, your stomach destroys them and almost none of it gets into your body — usually less than 1%.
Conclusion
- injectable delivery remains the most effective and reliable method for peptide absorption, especially for performance, recovery, and hormone optimization.
- Subcutaneous or SubQ injections are preferred for long-acting peptides like CJC-1295 with DAC, IGF-1 LR3, and BPC-157.
- Oral peptides face major challenges with digestion and absorption, but breakthroughs like oral semaglutide and permeation enhancers are making GI delivery more viable.
- Nanoparticle delivery systems and other advanced technologies (eg micro needles (only really viable for cosmetic peptides) hydrogels, transdermal patches) are rapidly emerging as non-invasive, next-generation options.
- Your choice of delivery method should match your peptide’s half-life, intended effect, comfort level, and compliance needs.
Overall inject and don't be a fucking bitch about it
