idk I'm I'ma allowed to do this but like I wanna help the community but idc if I get jfl and dnred I just want to be a helping hand (1 Viewer)

[5foot9cel]

give me your cycle or whatever and I'ma like help u out and shi im a PED expert but I'm not a larper or anything like I'm not tanner or something I'm just like a guy but its free advice so idk do what u want

 

[birthdefect]

give me your cycle or whatever and I'ma like help u out and shi im a PED expert but I'm not a larper or anything like I'm not tanner or something I'm just like a guy but its free advice so idk do what u want

do you believe modulation of the ihh pthrp feedback loop is worth the cancer risk

 

[hoodsickle]

We already have birthdefect, biomaxx and mandy we dont need you

 

[cordex]

550 test 6 iu gh 2 x 3iu a day, mast 300, proviron 50 before social events, 100mcg igf 1 lr3 before gym so 5 x a week.

 

[5foot9cel]

do you believe modulation of the ihh pthrp feedback loop is worth the cancer risk

bro there's no cancer risk just take abalo and pentox bro

 

[fent]

bro there's no cancer risk just take abalo and pentox bro

The goal of an SMO agonist is to ACTIVATE the IHH pathway,
Pentox elevates cAMP which inturn activates PKA
By using pentoxifylline to artificially boost cAMP and activate PKA, you are directly antagonizing the SMO agonist JFL

"im so high iq" your smart but you overestimate yourself

 

[birthdefect]

bro there's no cancer risk just take abalo and pentox bro

i asked you the question cus i thought you were stupid so i wanted to use weird words
anyways i did mean a smoothened agonist rather than a pthrp analogue, i agree with you that the cancer risk is likely negligible with abalo
with SAG i believe its probably significant and dangerous
SAG21k (or whichever one is the one that has increased bbb penetration) is literally used to study medulloblastoma
its used as a trigger for cancer

The goal of an SMO agonist is to ACTIVATE the IHH pathway,
Pentox elevates cAMP which inturn activates PKA
By using pentoxifylline to artificially boost cAMP and activate PKA, you are directly antagonizing the SMO agonist JFL

"im so high iq" your smart but you overestimate yourself

why would you take pentox? stop taking non selective drugs
pde3 inhibition is all you need, allows for cAMP and cGMP to accumulate in the plates in a beneficial zone specific way
and btw yall arent affording SAG or any of its variants

 

[birthdefect]

The goal of an SMO agonist is to ACTIVATE the IHH pathway,
Pentox elevates cAMP which inturn activates PKA
By using pentoxifylline to artificially boost cAMP and activate PKA, you are directly antagonizing the SMO agonist JFL

"im so high iq" your smart but you overestimate yourself

pretty sure cAMP accumulation is synergistic with abalo
he mentioned pthrp agonism rather than smo agonism

 

[Circadex]

We already have birthdefect, biomaxx and mandy we dont need you

Stop being over confident in members and welcome competition

 

[fent]

i asked you the question cus i thought you were stupid so i wanted to use weird words
anyways i did mean a smoothened agonist rather than a pthrp analogue, i agree with you that the cancer risk is likely negligible with abalo
with SAG i believe its probably significant and dangerous
SAG21k (or whichever one is the one that has increased bbb penetration) is literally used to study medulloblastoma
its used as a trigger for cancer

why would you take pentox? stop taking non selective drugs
pde3 inhibition is all you need, allows for cAMP and cGMP to accumulate in the plates in a beneficial zone specific way
and btw yall arent affording SAG or any of its variants

PDE3 mogs, SAG21K fucking suckkkks lol. Puermo mogs or however you spell it

 

[fent]

pretty sure cAMP accumulation is synergistic with abalo
he mentioned pthrp agonism rather than smo agonism

My reply was assuming he meant using those as viable ancillaries

 

[birthdefect]

PDE3 mogs, SAG21K fucking suckkkks lol. Puermo mogs or however you spell it

idk what peurmo is i cant lie

My reply was assuming he meant using those as viable ancillaries

i just woke up so that could be it but idk what this means i cant lie
he mentioned using abalo and pde4 inhibition synergistically, you mentioned smo agonists instead which arent the same
but it prob doesnt matter

 

[number1fakecel]

Stop being over confident in members and welcome competition

hoodsickles dead

 

[5foot9cel]

The goal of an SMO agonist is to ACTIVATE the IHH pathway,
Pentox elevates cAMP which inturn activates PKA
By using pentoxifylline to artificially boost cAMP and activate PKA, you are directly antagonizing the SMO agonist JFL

"im so high iq" your smart but you overestimate yourself

you don't want ihh its a hypertrophic signal, you WANT the camp mediated PKA because it increases pthrp

this is pathetic I mog U to hell
preserving the crucial proliferation pool is better than trying to maximize hypertrophic cell size, ESPECIALLY when the hypertrophic chondryctes don't express pth1r JFL so this feedback loop is not present in the hz

kys You IQlet Hopefully

 

[5foot9cel]

i asked you the question cus i thought you were stupid so i wanted to use weird words
anyways i did mean a smoothened agonist rather than a pthrp analogue, i agree with you that the cancer risk is likely negligible with abalo
with SAG i believe its probably significant and dangerous
SAG21k (or whichever one is the one that has increased bbb penetration) is literally used to study medulloblastoma
its used as a trigger for cancer

why would you take pentox? stop taking non selective drugs
pde3 inhibition is all you need, allows for cAMP and cGMP to accumulate in the plates in a beneficial zone specific way
and btw yall arent affording SAG or any of its variants

ANOTHER IQlet talking about no selective fucking drugs wtf

our best drug for height is known for having 0 selectivity jfl

 

[5foot9cel]

Stop being over confident in members and welcome competition

See I love this nigga I remember in Nov this guy was being so like open and shit like it piss me off sometimes like who this guy thinks he is but like all in all like he be fostering some bs like BFR and orka did bro shi brings a tear to my eye

 

[5foot9cel]

We already have birthdefect, biomaxx and mandy we dont need you

idk him, EXTREMELY low IQ where he should kill himself out of hopelessness, idk him

you do need me motherfucker look at you stupid piece of shit I iqmog u all

 

[5foot9cel]

give me your cycle or whatever and I'ma like help u out and shi im a PED expert but I'm not a larper or anything like I'm not tanner or something I'm just like a guy but its free advice so idk do what u want

yo I'm going to try to go from 5 foot 8.5 at 17 to 6 foot 2 by september Next year wish me luck

 

[birthdefect]

you don't want ihh its a hypertrophic signal, you WANT the camp mediated PKA because it increases pthrp

this is pathetic I mog U to hell
preserving the crucial proliferation pool is better than trying to maximize hypertrophic cell size, ESPECIALLY when the hypertrophic chondryctes don't express pth1r JFL so this feedback loop is not present in the hz

kys You IQlet Hopefully

agreed, i dont see a lot on preserving and rejuvenating the resting and proliferating zones

ANOTHER IQlet talking about no selective fucking drugs wtf

our best drug for height is known for having 0 selectivity jfl

at the time i hadnt researched pentox much, its actually pretty good i believe
i do wonder tho, if pde4i preserves proliferating chondrocytes through the cAMP and pde3i maximises hypertrophy, whats the result in combining them
a bit of both? sounds super ideal tbh

best known drug you mean hgh? fair, vosoritide is up there as well and its known for being extremely selective

 

[5foot9cel]

agreed, i dont see a lot on preserving and rejuvenating the resting and proliferating zones

at the time i hadnt researched pentox much, its actually pretty good i believe
i do wonder tho, if pde4i preserves proliferating chondrocytes through the cAMP and pde3i maximises hypertrophy, whats the result in combining them
a bit of both? sounds super ideal tbh

best known drug you mean hgh? fair, vosoritide is up there as well and its known for being extremely selective

best known drug is Tyra best available drug is erda

"
agreed, i dont see a lot on preserving and rejuvenating the resting and proliferating zones
"

This is like the only way to increase height WTF are u talking about its should be the only goal

 

[5foot9cel]

best known drug is Tyra best available drug is erda

"
agreed, i dont see a lot on preserving and rejuvenating the resting and proliferating zones
"

This is like the only way to increase height WTF are u talking about its should be the only goal

Also wtf is wrong with this RPO bullshit bro
wtf is the obsession with cAMP -> pka -> pthrp it has virtually no in vivo data

like I get in vitro data is great but we have like 2 in vivo

 

[5foot9cel]

Also wtf is wrong with this RPO bullshit bro
wtf is the obsession with cAMP -> pka -> pthrp it has virtually no in vivo data

like I get in vitro data is great but we have like 2 in vivo

and these two don't even show shit tbh one is a grafting study and the other is a FAH study of like 0.1mm difference which is significant but not to like the degree

 

[fent]

you don't want ihh its a hypertrophic signal, you WANT the camp mediated PKA because it increases pthrp

this is pathetic I mog U to hell
preserving the crucial proliferation pool is better than trying to maximize hypertrophic cell size, ESPECIALLY when the hypertrophic chondryctes don't express pth1r JFL so this feedback loop is not present in the hz

kys You IQlet Hopefully

ur right unfortunatley

 

[Dragon]

you don't want ihh its a hypertrophic signal, you WANT the camp mediated PKA because it increases pthrp

this is pathetic I mog U to hell
preserving the crucial proliferation pool is better than trying to maximize hypertrophic cell size, ESPECIALLY when the hypertrophic chondryctes don't express pth1r JFL so this feedback loop is not present in the hz

kys You IQlet Hopefully

bro took 2 and a half week for his reply lols

 

[5foot9cel]

ur right unfortunatley

naturally

 

[fent]

naturally

Respond to PMs

 

[5foot9cel]

Respond to PMs

you reacted jfl to my post fuck you bro asking me for help

 

[fent]

you reacted jfl to my post fuck you bro asking me for help

misclick, theres a reason i removed it. And i am asking you for help your obviouslly more knowledgeable then me

 

[BakedSock51]

naturally

the hairs on my forearm stood up reading ts, cold

 

[birthdefect]

This is like the only way to increase height WTF are u talking about its should be the only goal

yea im still correct
niggas take a shit ton of androgens and call it heightmaxxing

 

[austin.f7]

give me your cycle or whatever and I'ma like help u out and shi im a PED expert but I'm not a larper or anything like I'm not tanner or something I'm just like a guy but its free advice so idk do what u want

if you help me and offer advice ill pay.

 

[buzzy]

does anyone know why this guy was banned??

 

[fent]

does anyone know why this guy was banned??

i think dysregulated banned him, this guy was very high iq nonetheless