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Been getting quite into neuro stuff recently so thought id write this out since the shitting hieghtmaxxing shit took up so much time js to DISSAPEAR
Depending on dosage, complete mitigation of side effects is not always possible. However, by using targeted interventions, neurological risk can be reduced as much as realistically achievable.
what actually happens to the brain under androgen exposure?
Androgens disrupt multiple neural signaling and maintenance pathways. The most relevant effects are outlined right here.
These changes can significantly impair cognition by degrading learning capacity, attention, memory consolidation, problem-solving, executive function, and intrinsic neuroprotection. Risk is also elevated for depression, anxiety, ADHD-like symptoms, Alzheimer’s disease, Parkinson’s disease, and cerebrovascular events.
so what compounds can we use to reverse this damage?
ACD85-6 binds to Trk-type receptors, increasing BDNF signaling, synaptic plasticity, neurogenesis, and neurotrophin-3, while simultaneously exerting anti-inflammatory effects.
Pennylon upregulates the HSPA1 gene, improving insulin sensitivity and lipid handling not only systemically but within neural tissue as well. It strongly supports cellular resilience and enhances resistance to oxidative stress.
SS-31 enhances mitochondrial efficiency, improving apoptotic regulation and enabling tighter control of reactive oxygen species.
You will also need an antioxidant protocol timed around androgen exposure, with the most effective options listed-
DHA
Glutathione
NAC
Astaxanthin
Carnosic acid
Vitamin C
High-dose melatonin may be implemented, ideally reserved for periods of very high androgen exposure.
Next, if concerns such as growth plate closure, fluid retention, or gynecomastia are secondary, estrogen should be maintained within range—preferably toward the higher end. Estrogen is critical for the brain: it supports synaptic plasticity, promotes neurogenesis, functions as a powerful neural antioxidant, and stabilizes neurotransmitter regulation
Androgens can be neurologically damaging, but with structured protocol design and informed compound selection, the magnitude of harm can be meaningfully constrained.
Yeah shit was crazy no tales i swear
I was in the train for 5 min and there was a big bump, strain stopped they let us walk to the stadion and p[ol,ice where everywhere
mirin guide
this is further evidence(to me atleast) that the benefits of androgens during puberty just arent worth it compared to all the ancillaries needed and the fact that they speed up chondrocyte maturation significantly
i guess we'll see until Zagro on org posts his bone age result
i mentioned him here but honestly have no idea if its the same person or a different Zagro who's also roiding
Androgens wont affect your bone age or accelerate anything, it needs to “accelerate” it in order for you to growth like you need endochondral ossification to occur for growth and without estradiol it wont do any detrimental shit. Androgens during puberty are crucial bro and you don’t need the whole ancillary stack
The bone aging mechanism is so mild when you put things into perspective and if you don’t suddenly hop off aromatase inhibitors nothing will happen
I will delay the x-ray for a while or skip it altogether probably and its me not some other zagro
Androgens wont affect your bone age or accelerate anything, it needs to “accelerate” it in order for you to growth like you need endochondral ossification to occur for growth and without estradiol it wont do any detrimental shit. Androgens during puberty are crucial bro and you don’t need the whole ancillary stack
The bone aging mechanism is so mild when you put things into perspective and if you don’t suddenly hop off aromatase inhibitors nothing will happen
I will delay the x-ray for a while or skip it altogether probably and its me not some other zagro
they increase how quickly chondrocytes go from proliferating to hypertrophying as well do they not? ideally i would try to get as many chondrocytes to proliferate as possible and then use androgens afterwards. estradiol itself affects future daughter chondrocytes through genomic signalling even if you've zeroed it out, but im not sure if androgens also do this
please dont delay or skip the xray we must know the result fr
Yeah shit was crazy no tales i swear
I was in the train for 5 min and there was a big bump, strain stopped they let us walk to the stadion and p[ol,ice where everywhere
Been getting quite into neuro stuff recently so thought id write this out since the shitting hieghtmaxxing shit took up so much time js to DISSAPEAR
Depending on dosage, complete mitigation of side effects is not always possible. However, by using targeted interventions, neurological risk can be reduced as much as realistically achievable.
what actually happens to the brain under androgen exposure?
Androgens disrupt multiple neural signaling and maintenance pathways. The most relevant effects are outlined right here.
These changes can significantly impair cognition by degrading learning capacity, attention, memory consolidation, problem-solving, executive function, and intrinsic neuroprotection. Risk is also elevated for depression, anxiety, ADHD-like symptoms, Alzheimer’s disease, Parkinson’s disease, and cerebrovascular events.
so what compounds can we use to reverse this damage?
ACD85-6 binds to Trk-type receptors, increasing BDNF signaling, synaptic plasticity, neurogenesis, and neurotrophin-3, while simultaneously exerting anti-inflammatory effects.
Pennylon upregulates the HSPA1 gene, improving insulin sensitivity and lipid handling not only systemically but within neural tissue as well. It strongly supports cellular resilience and enhances resistance to oxidative stress.
SS-31 enhances mitochondrial efficiency, improving apoptotic regulation and enabling tighter control of reactive oxygen species.
You will also need an antioxidant protocol timed around androgen exposure, with the most effective options listed-
DHA
Glutathione
NAC
Astaxanthin
Carnosic acid
Vitamin C
High-dose melatonin may be implemented, ideally reserved for periods of very high androgen exposure.
Next, if concerns such as growth plate closure, fluid retention, or gynecomastia are secondary, estrogen should be maintained within range—preferably toward the higher end. Estrogen is critical for the brain: it supports synaptic plasticity, promotes neurogenesis, functions as a powerful neural antioxidant, and stabilizes neurotransmitter regulation
Androgens can be neurologically damaging, but with structured protocol design and informed compound selection, the magnitude of harm can be meaningfully constrained.
they increase how quickly chondrocytes go from proliferating to hypertrophying as well do they not? ideally i would try to get as many chondrocytes to proliferate as possible and then use androgens afterwards. estradiol itself affects future daughter chondrocytes through genomic signalling even if you've zeroed it out, but im not sure if androgens also do this
please dont delay or skip the xray we must know the result fr
Its not as significant its a mild push and the trade-off is good also if your bone age is above like 14-15 doing both a proliferative and hypertrophic “stack” would be hard as you wont have the time to do so, and androgens promote both proliferation and hypertrophy. Its most likely context-dependent and you still would benefit from AR activation but not as high
I don’t really have time now i have to delay it man
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Mandy can u share the things u took ?
Circadex
LogitechG502
Godveil Heir ummmm who else can i tag
birthdefect
Primalwontsaveme
ronniechap
biomax
hide
and your cute dark yellow name 
you can change the profile picture if you want looking for a new one rn
