What it is and how to mitigate it.
This Guide should not be heeded as medical advice, as I am not a medical professional, this is purely theoretical, If you are harmed by this guide, I am not liable, though I will take input from those who use it(if any).
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THEORETICAL LIVER PROTECTION METHOD
I do not know how one would acquire UDCA, but by far it is the most superior liver protection compound to ever exist. I would also recommend Prednisolone, as combined they have 98% liver recovery rates, and ensure to ward off liver enzyme damage, however, when added with synergistic NAC, I hypothesize that You could run a cycle with very very minimal liver effects thanks to this hepatoprotective substance list. As for dosages, standards can be found online, as it is very dependent on body composition.
Thank you,
The wizard
ps: i typed this on my iphone so the formatting is prolly shit
First, we must define Hepatotoxicity, which is an acute or chronic liver injury secondary to drugs or herbal compounds. It is noted that it is difficult for a medical professional to diagnose due to its nature resembling a hepatobiliary disorder. The principle and current treatment method is the removal of the offending substance, which is usually dictated if the subject crosses the boundary of Hy’s Law, meaning that if the user of substance has hepatocellular injury and jaundice, his estimated mortality rate exceeds 10 percent, possibly lying around 50 ish percent, as the study never distinguished between how many died and needed a liver transplant, fusing the two into a statistical category. If you discontinue the substance, the recommended method, you will have a >90% chance of recovery. However, in this guide, I will explore theoretical options that will allow you to continue said liver damaging substance, and how to mitigate its effects on the liver.
This Guide should not be heeded as medical advice, as I am not a medical professional, this is purely theoretical, If you are harmed by this guide, I am not liable, though I will take input from those who use it(if any).
How to recognize hepatocellular injury
Jaundice is the main recognizable symptom, but many can be asymptomatic to hepatocellular injury, and the only other definitive way of telling so is by getting a blood test, and checking for ALT(Alanine Transaminase), AST(Aspartate Transaminase), and ALP(Alkaline phosphatase), As well as GGT(Gamma Glutamyl Transferase). To get a test of this kind, you must order a Common Metabolic Panel. However, your substance use will be easily determined by the levels of these enzymes, which as the liver is stressed, release into the bloodstream. This is a surefire way to recognize Hepatotoxicity, And Hepatocellular injury, though they are usually synchronous. These are the only 2 surefire methods to determine Hepatotoxicity.
Jaundice is the main recognizable symptom, but many can be asymptomatic to hepatocellular injury, and the only other definitive way of telling so is by getting a blood test, and checking for ALT(Alanine Transaminase), AST(Aspartate Transaminase), and ALP(Alkaline phosphatase), As well as GGT(Gamma Glutamyl Transferase). To get a test of this kind, you must order a Common Metabolic Panel. However, your substance use will be easily determined by the levels of these enzymes, which as the liver is stressed, release into the bloodstream. This is a surefire way to recognize Hepatotoxicity, And Hepatocellular injury, though they are usually synchronous. These are the only 2 surefire methods to determine Hepatotoxicity.
CORTICOSTEROIDS
Corticosteroids can reduce inflammation, specifically Prednisolone, and Prednisone, Can ensure Liver recovery by exerting immunosuppressive and antiinflammatory effects, preventing T-Cells from attacking liver tissue, which occurs with moderate to severe hepatotoxicity, And is a very severe sign someone needs a liver transplant, and is in liver failure, or very close to it. They could, with continuing usage while on cycle, minimize the liver damage itself
Corticosteroids can reduce inflammation, specifically Prednisolone, and Prednisone, Can ensure Liver recovery by exerting immunosuppressive and antiinflammatory effects, preventing T-Cells from attacking liver tissue, which occurs with moderate to severe hepatotoxicity, And is a very severe sign someone needs a liver transplant, and is in liver failure, or very close to it. They could, with continuing usage while on cycle, minimize the liver damage itself
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NAC
N-Acetylcysteine, better known as NAC, is a modified version of L-cysteine, the amino acid. Its Mechanism is it replenishes Glutathione levels, which protects cells from liver damage caused by toxins, And it lowers oxidative stress and lowers elevated levels of liver enzymes. It also Neutralizes Toxic Free Radicals. This is by far the most accessible liver protection supplement/compound, and should be ran with any potent androgenic cycle regardless of compound.
N-Acetylcysteine, better known as NAC, is a modified version of L-cysteine, the amino acid. Its Mechanism is it replenishes Glutathione levels, which protects cells from liver damage caused by toxins, And it lowers oxidative stress and lowers elevated levels of liver enzymes. It also Neutralizes Toxic Free Radicals. This is by far the most accessible liver protection supplement/compound, and should be ran with any potent androgenic cycle regardless of compound.
Ursodeoxycholic acid (UDCA)
This Chemical, UDCA, is widely used in Liver damage repair, as its mechanism of Action is quite literally a plethora of Hepatoprotective activities, such as Inhibition of Cytokines signaling for T-cells to activate and proliferate against liver enzymes, It controls ER stress, which also stops Apoptosis, It also replaces cytotoxic bile fluids with itself, and therefore reduces the acidity of the liver environment, reducing stress on the liver enzymes, as cytotoxic bile induces necrosis and apoptosis simultaneously, and this is not even a tenth of UDCA’s total hepatoprotective functions. It is the best chemical out there for liver protection while on cycle.
This Chemical, UDCA, is widely used in Liver damage repair, as its mechanism of Action is quite literally a plethora of Hepatoprotective activities, such as Inhibition of Cytokines signaling for T-cells to activate and proliferate against liver enzymes, It controls ER stress, which also stops Apoptosis, It also replaces cytotoxic bile fluids with itself, and therefore reduces the acidity of the liver environment, reducing stress on the liver enzymes, as cytotoxic bile induces necrosis and apoptosis simultaneously, and this is not even a tenth of UDCA’s total hepatoprotective functions. It is the best chemical out there for liver protection while on cycle.
THEORETICAL LIVER PROTECTION METHOD
I do not know how one would acquire UDCA, but by far it is the most superior liver protection compound to ever exist. I would also recommend Prednisolone, as combined they have 98% liver recovery rates, and ensure to ward off liver enzyme damage, however, when added with synergistic NAC, I hypothesize that You could run a cycle with very very minimal liver effects thanks to this hepatoprotective substance list. As for dosages, standards can be found online, as it is very dependent on body composition.
Thank you,
The wizard
ps: i typed this on my iphone so the formatting is prolly shit
