[Zynx]

Dutasteride

Dutasteride inhibits type I and II 5-α-reductase, achieving deeper DHT suppression than finasteride. Trials report greater increases in hair counts and cosmetic improvement, particularly in advanced thinning. It is a high-potency pharmacologic option used when maximal DHT control is prioritized.

Spoiler: Mechanism

Dual isoenzyme inhibition (types I/II) serum DHT suppression often (90%). Type I 5-AR expression in scalp/sebaceous glands adds theoretical advantage for vertex and frontal preservation.

Spoiler: Evidence

Head-to-head and dose-ranging studies demonstrate superior efficacy vs. finasteride on hair counts and investigator assessments. Benefits accrue through 6–12 months with continued gains thereafter.

Spoiler: Notes / Stack

Often used after inadequate response to finasteride. Stack with minoxidil; keep ketoconazole as adjunct for scalp environment. Consider medical supervision given depth of systemic DHT reduction.

Studies/References

Comparison of 2.6- and 1.4-mm imaging probes for confocal laser endomicroscopy of the urinary tract - PubMed

The optical specifications of the 2.6-mm probe are more suitable for distinguishing urinary tract histopathology. Further design optimization to improve resolution and additional validation of the diagnostic accuracy of the smaller probe are needed to help extend application of pCLE for optical...

pubmed.ncbi.nlm.nih.gov

https://pubmed.ncbi.nlm.nih.gov/24422779/

Successful amplification of extremely GC-rich promoter regions using a novel 'slowdown PCR' technique - PubMed

Here we show that 'Slowdown' PCR is a versatile method not only for amplification of extremely GC-rich regions but also for routine DNA diagnostics and pharmacogenetics for templates with different annealing temperatures.

pubmed.ncbi.nlm.nih.gov

 

[Shiksa]

gpt slop

 

[Zynx]

gpt slop

isn't gpt jfl

 

[Hal.-.106h]

Dutasteride

Dutasteride inhibits type I and II 5-α-reductase, achieving deeper DHT suppression than finasteride. Trials report greater increases in hair counts and cosmetic improvement, particularly in advanced thinning. It is a high-potency pharmacologic option used when maximal DHT control is prioritized.

Spoiler: Mechanism

Dual isoenzyme inhibition (types I/II) serum DHT suppression often (90%). Type I 5-AR expression in scalp/sebaceous glands adds theoretical advantage for vertex and frontal preservation.

Spoiler: Evidence

Head-to-head and dose-ranging studies demonstrate superior efficacy vs. finasteride on hair counts and investigator assessments. Benefits accrue through 6–12 months with continued gains thereafter.

Spoiler: Notes / Stack

Often used after inadequate response to finasteride. Stack with minoxidil; keep ketoconazole as adjunct for scalp environment. Consider medical supervision given depth of systemic DHT reduction.

Studies/References

Comparison of 2.6- and 1.4-mm imaging probes for confocal laser endomicroscopy of the urinary tract - PubMed

The optical specifications of the 2.6-mm probe are more suitable for distinguishing urinary tract histopathology. Further design optimization to improve resolution and additional validation of the diagnostic accuracy of the smaller probe are needed to help extend application of pCLE for optical...

pubmed.ncbi.nlm.nih.gov

https://pubmed.ncbi.nlm.nih.gov/24422779/

Successful amplification of extremely GC-rich promoter regions using a novel 'slowdown PCR' technique - PubMed

Here we show that 'Slowdown' PCR is a versatile method not only for amplification of extremely GC-rich regions but also for routine DNA diagnostics and pharmacogenetics for templates with different annealing temperatures.

pubmed.ncbi.nlm.nih.gov

Good thread

 

[Hal.-.106h]

Bump

 

[Shiksa]

shit account shit thread shit everything

 

[Hal.-.106h]

shit account shit thread shit everything

Watch your tone boiii

 

[Orc]

I think you guys should stick to this website with your AI slop.

 

[Hal.-.106h]

I think you guys should stick to this website with your AI slop.

@Zynx see what did I tell u everyone thinks we are using AI

 

[Zynx]

I think you guys should stick to this website with your AI slop.

at you thinking this is AI

 

[proex]

I think you guys should stick to this website with your AI slop.

tbf with idkmanimao it's true but i made very high iq threads on @proex on .org, shame all of them are delted by numb

 

[Shiksa]

I think you guys should stick to this website with your AI slop.

This is gpt slop unban me on org so I make good threads

 

[Hal.-.106h]

This is gpt slop unban me on org so I make good threads

Lmao

 

[Tumor]

Didn't read but high iq