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Guide Dutasteride Guide

Zynx

Iron
Joined
Aug 19, 2025
Posts
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Dutasteride

Dutasteride inhibits type I and II 5-α-reductase, achieving deeper DHT suppression than finasteride. Trials report greater increases in hair counts and cosmetic improvement, particularly in advanced thinning. It is a high-potency pharmacologic option used when maximal DHT control is prioritized.


Dual isoenzyme inhibition (types I/II) serum DHT suppression often (90%). Type I 5-AR expression in scalp/sebaceous glands adds theoretical advantage for vertex and frontal preservation.

Head-to-head and dose-ranging studies demonstrate superior efficacy vs. finasteride on hair counts and investigator assessments. Benefits accrue through 6–12 months with continued gains thereafter.

Often used after inadequate response to finasteride. Stack with minoxidil; keep ketoconazole as adjunct for scalp environment. Consider medical supervision given depth of systemic DHT reduction.

Studies/References

https://pubmed.ncbi.nlm.nih.gov/21568756/
https://pubmed.ncbi.nlm.nih.gov/24422779/
https://pubmed.ncbi.nlm.nih.gov/14646694/
 

Skywalker

Fortnite and ice cream 😹✌️
Joined
Aug 21, 2025
Posts
23
Reputation
385
Dutasteride

Dutasteride inhibits type I and II 5-α-reductase, achieving deeper DHT suppression than finasteride. Trials report greater increases in hair counts and cosmetic improvement, particularly in advanced thinning. It is a high-potency pharmacologic option used when maximal DHT control is prioritized.


Dual isoenzyme inhibition (types I/II) serum DHT suppression often (90%). Type I 5-AR expression in scalp/sebaceous glands adds theoretical advantage for vertex and frontal preservation.

Head-to-head and dose-ranging studies demonstrate superior efficacy vs. finasteride on hair counts and investigator assessments. Benefits accrue through 6–12 months with continued gains thereafter.

Often used after inadequate response to finasteride. Stack with minoxidil; keep ketoconazole as adjunct for scalp environment. Consider medical supervision given depth of systemic DHT reduction.

Studies/References

https://pubmed.ncbi.nlm.nih.gov/21568756/
https://pubmed.ncbi.nlm.nih.gov/24422779/
https://pubmed.ncbi.nlm.nih.gov/14646694/
Good thread
 

Starborn

from org .org/@autism (Formerly @autisticntmaxer)
Joined
Oct 15, 2025
Posts
81
Reputation
124
Dutasteride

Dutasteride inhibits type I and II 5-α-reductase, achieving deeper DHT suppression than finasteride. Trials report greater increases in hair counts and cosmetic improvement, particularly in advanced thinning. It is a high-potency pharmacologic option used when maximal DHT control is prioritized.


Dual isoenzyme inhibition (types I/II) serum DHT suppression often (90%). Type I 5-AR expression in scalp/sebaceous glands adds theoretical advantage for vertex and frontal preservation.

Head-to-head and dose-ranging studies demonstrate superior efficacy vs. finasteride on hair counts and investigator assessments. Benefits accrue through 6–12 months with continued gains thereafter.

Often used after inadequate response to finasteride. Stack with minoxidil; keep ketoconazole as adjunct for scalp environment. Consider medical supervision given depth of systemic DHT reduction.

Studies/References

https://pubmed.ncbi.nlm.nih.gov/21568756/
https://pubmed.ncbi.nlm.nih.gov/24422779/
https://pubmed.ncbi.nlm.nih.gov/14646694/
Zynx Zynx
Capture.PNG

why does this shit say 2 million jfl
 
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