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Do you notice your GLP-1s effect attenuate over time (3 Viewers)

Do you notice your GLP-1s effect attenuate over time

surgerymax

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  • #1
Weaker appetite suppression with months of use , etc.
 
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  • #2
nobody understands ts bro ask AI not some retards in a looksmaxxing forum
 

Daker

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  • #3
1780681405311.png


Ahhhh
 

Dexter

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Daker

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Dexter

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Alyx

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  • #7
Weaker appetite suppression with months of use , etc.
When I started drinking my Semen for Test, I noticed its appetite suppression starts to wear off in a couple of months. (It also acts as a GLP 1)
 

Daker

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  • #8

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Iron
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  • #9
Weaker appetite suppression with months of use , etc.
Yeah unfortunately, I remember when I first started at just 2mg it hit me like a truck and I looked at food with disgust. Thinking of cycling off soon to allow my body sensitive back to it. While I’m still way less hungry and eat much less compared to before I ever hopped on I miss how much more potent it felt
 

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Iron
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  • #10
Weaker appetite suppression with months of use , etc.
Was thinking of also using something like tirz while I’m off since it’s only a double agonist. Nardicus said how due to Reta being a triple agonist you expend much more energy which in turn brings more hunger. As you increase the dose I imagine the effect increases as well. Reta still mogs 👌
 

surgerymax

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  • #11
Yeah unfortunately, I remember when I first started at just 2mg it hit me like a truck and I looked at food with disgust. Thinking of cycling off soon to allow my body sensitive back to it. While I’m still way less hungry and eat much less compared to before I ever hopped on I miss how much more potent it felt
there seems to be a very good way to keep ur appetite nuked for basically all year besides about 12 weeks , might make a thread on it
Was thinking of also using something like tirz while I’m off since it’s only a double agonist. Nardicus said how due to Reta being a triple agonist you expend much more energy which in turn brings more hunger. As you increase the dose I imagine the effect increases as well. Reta still mogs 👌
tirz has more potent appetite suppression in general due to having a higher affinity for GLP-1 , but also yes reta can be paradoxical at higher doses as u expend more energy , not sure how much this glucagon expenditure actually is though but at 5mg and lower you should be fine , based off the data reta is the most individual fat loss agent ultimately but with tirz if u can nuke appetite harder and use other things like clen , mirabegron , t3 and so on to raise caloric expenditure prob does mog , on the flip side if u can keep ur cals in check with these + reta it would be even better ,

If your response has been attenuated u need to resensitise or hit different pathways , try throwing in some cagri
 

Nardicus

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  • #12
Was thinking of also using something like tirz while I’m off since it’s only a double agonist. Nardicus said how due to Reta being a triple agonist you expend much more energy which in turn brings more hunger. As you increase the dose I imagine the effect increases as well. Reta still mogs 👌
Yea when I touched 6mg it dint feel supper strong at all,

like going from 2mg -> 4mg felt like stronger suppression for me, but from 4 -> 6 it dint feel as a strong bump than my original bump
I def think it's the Glucagon making the body compensating for extra cal being burned thus increasing hunger signals for sure.

when I hop off DNP, Imma jus go back to Triz since I wont really need the Glucagon anymore at all, n would rather jus maintain
 

surgerymax

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Yea when I touched 6mg it dint feel supper strong at all,

like going from 2mg -> 4mg felt like stronger suppression for me, but from 4 -> 6 it dint feel as a strong bump than my original bump
I def think it's the Glucagon making the body compensating for extra cal being burned thus increasing hunger signals for sure.

when I hop off DNP, Imma jus go back to Triz since I wont really need the Glucagon anymore at all, n would rather jus maintain
I believe with this protocol you should be able to keep appetite nuked basically all year

12 weeks on GLP-1 of your choice titrating doses up as per needed

8 weeks off GLP-1s to allow for resensitisation of receptors and during this time run cagri + tesofensine (can throw in LDN or Bupropion if needed) to keep appetite curbed , staying at LEAST maintenance should still be very easy as you're hitting receptors freshly , but importantly this should basically destroy any kind of withdrawal symptoms too

then back on glp1s for 12 weeks rinse and repeat

Ideally if you aren't having issues with the appetite suppression getting too weak then stay on tirz/reta all year for the insulin sensitivity + liver benefits and so on regardless most people should be chilling without compounds that spike the fuck out of ur appetite like tren eq and shit and can just run reta cagri year round


Also would be on replacement doses of t3 all year so dont have to deal with any bullshit metabolic adaptations of being lean for a long time
 

Aiphok

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surgerymax

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