Theory Bee stings for norwood ?? (1 Viewer)

[Biomaxx]

How can bee venom be utilised for stopping hair loss and promoting hair growth.

I stumbled upon a social media post, this guy went out and placed angry bees on his peaks for the purpose of getting stung (obviously). This intrigued me so i thought I'd go do my own research

Bee venom directly inhibits local 5a-reductase ( the enzyme that converts testosterone to DHT (1 of the main causes for hair loss)).

This happens through a peptide found in bee vemom called mellitin .
(then enhanced by PLA2)

mellitin
mellitin is insanely and underrattedly useful for the context of local hair growth and loss reduction. But how?

Along with inhibiting 5a-reductase it-
increases igfr sensitivity
upregulates VEGF (vascular endothelial growth factor )
Upregulates fgf-2 and -7 (fibroblast growth)
ASCs release (cell migration and proliferation, endothelial growth, osteogenesis)

Delays catagen entry (regression)
prolongs anagen duration (growth)

Spoiler: Studies

https://pmc.ncbi.nlm.nih.gov/articles/PMC6669657/?sharetype=link
https://pmc.ncbi.nlm.nih.gov/articles/PMC10892121/?sharetype=link
https://pubmed.ncbi.nlm.nih.gov/27040904/?sharetype=link
Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression - PubMed https://share.google/f8tlhYaMdoMbFRqcj
Bee Venom Stimulates Growth Factor Release from Adipose-Derived Stem Cells to Promote Hair Growth - PubMed https://share.google/sbesCPbUu0uZPEm0Y

PLA2
PLA2 (found to be 12% of bee venom) plays a gaint role in how bioactive mellitin is and how cells react to it

5-ar is meberane-associated, meaning intacellular penetration is needed for inhibition. This is exactly what PLA2 helps with, it expands what was a narrow doorway into intracullar level, improving mellitin access.

PLA2 is the reason you get a bump after a bee sting, it causes an inflammatory response. Which increases blood flow and growth factor locally.

——————————————————

Now im not telling you to go get stung bees.
This mechanism can be triggered with bee venom and a derma planner (1mm)

Bee venom can be rather expensive ($300+)
Who says you can't go collect it yourself ?

Get a glass cup with a cheese cloth over it
stun bees by hitting/smoking them
Place agitated be on cloth (holding both wings)
Done - although this would be a long process and you would likely get stung

——————————————
In reality practice this would be rather unpractical or expensive.

Fun idea tho

Until next time
biomaxx
​

 

[Biomaxx]

Ik i sound like a robot but I promise im js faded

 

[nineteen]

How can bee venom be utilised for stopping hair loss and promoting hair growth.

I stumbled upon a social media post, this guy went out and placed angry bees on his peaks for the purpose of getting stung (obviously). This intrigued me so i thought I'd go do my own research

Bee venom directly inhibits local 5a-reductase ( the enzyme that converts testosterone to DHT (1 of the main causes for hair loss)).

This happens through a peptide found in bee vemom called mellitin .
(then enhanced by PLA2)

View attachment 36483

mellitin
mellitin is insanely and underrattedly useful for the context of local hair growth and loss reduction. But how?

Along with inhibiting 5a-reductase it-
increases igfr sensitivity
upregulates VEGF (vascular endothelial growth factor )
Upregulates fgf-2 and -7 (fibroblast growth)
ASCs release (cell migration and proliferation, endothelial growth, osteogenesis)

Delays catagen entry (regression)
prolongs anagen duration (growth)

Spoiler: Studies

https://pmc.ncbi.nlm.nih.gov/articles/PMC6669657/?sharetype=link
https://pmc.ncbi.nlm.nih.gov/articles/PMC10892121/?sharetype=link
https://pubmed.ncbi.nlm.nih.gov/27040904/?sharetype=link
Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression - PubMed https://share.google/f8tlhYaMdoMbFRqcj
Bee Venom Stimulates Growth Factor Release from Adipose-Derived Stem Cells to Promote Hair Growth - PubMed https://share.google/sbesCPbUu0uZPEm0Y

PLA2
PLA2 (found to be 12% of bee venom) plays a gaint role in how bioactive mellitin is and how cells react to it

5-ar is meberane-associated, meaning intacellular penetration is needed for inhibition. This is exactly what PLA2 helps with, it expands what was a narrow doorway into intracullar level, improving mellitin access.

PLA2 is the reason you get a bump after a bee sting, it causes an inflammatory response. Which increases blood flow and growth factor locally.

——————————————————

Now im not telling you to go get stung bees.
This mechanism can be triggered with bee venom and a derma planner (1mm)

Bee venom can be rather expensive ($300+)
Who says you can't go collect it yourself ?

Get a glass cup with a cheese cloth over it
stun bees by hitting/smoking them
Place agitated be on cloth (holding both wings)
Done - although this would be a long process and you would likely get stung

——————————————
In reality practice this would be rather unpractical or expensive.

Fun idea tho

Until next time
biomaxx
​

will read later

mirin

 

[FoidSlayer]

Interesting

I read it, but lowk didn't retain alot of Info tbh

Mirin tho

 

[Circadex]

Hair cafe is coming

 

[Tismo]

if it works its still cheaper than going to turkey IF it works, interesting thread

 

[Godveil Heir]

if it works its still cheaper than going to turkey

No it's not

it's 100x more expensive lol

not happening anytime soon
maybe after some decades when they can seperate the pro-hair compound from bee venom or synthesize it

 

[Tismo]

No it's not

it's 100x more expensive lol

not happening anytime soon
maybe after some decades when they can seperate the pro-hair compound from bee venom or synthesize it

everything costs you min 3k pretty sure you could get a ton of this for 3k
but i agree if it worked now we would already know about it balding is probably the thing most researched in terms of looks

 

[Biomaxx]

everything costs you min 3k pretty sure you could get a ton of this for 3k
but i agree if it worked now we would already know about it balding is probably the thing most researched in terms of looks

Maybe do js get bees to sting you

 

[Godveil Heir]

everything costs you min 3k pretty sure you could get a ton of this for 3k
but i agree if it worked now we would already know about it balding is probably the thing most researched in terms of looks

If you're talking about with stem cells and stuff, it'll definitely cost way more

if you're just talking about venom, it won't even be a substitute for hair transplant
just for minoxidil

and minox/duta are way cheaper than bee venom

 

[Godveil Heir]

 

[Tismo]

View attachment 36507

i dont really see whats happening here but i agree with what you said

 

[Biomaxx]

i dont really see whats happening here but i agree with what you said

Dont use minox or youll turn blue

 

[Godveil Heir]

i dont really see whats happening here but i agree with what you said

just a study comparing nothing vs 2% minox vs bee venom at different concentrations, for hair growth

 

[Biomaxx]

View attachment 36507

Yoink

 

[Tismo]

Yoink

making up sources on the go

 

[Godveil Heir]

Yoink

It was literally from the studies you mentioned in this thread, lol.
If you had read it, you would have known jfl.

Title "Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression"
https://www.jstage.jst.go.jp/article/bpb/39/6/39_b16-00158/_html/-char/en

 

[Biomaxx]

It was literally from the studies you mentioned in this thread, lol.
If you had read it, you would have known jfl.

Title "Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression"
https://www.jstage.jst.go.jp/article/bpb/39/6/39_b16-00158/_html/-char/en

I skimmed

 

[Godveil Heir]

I skimmed

it was a picture

 

[Tismo]

I skimmed

second biomaxx expose thread incoming

 

[Biomaxx]

second biomaxx expose thread incoming

Nga i js skimmed through the studies and got my own photo what i js sat for like 45 mins writing this out

 

[Tismo]

Nga i js skimmed through the studies and got my own photo what i js sat for like 45 mins writing this out

i was just pulling your leg

 

[Biomaxx]

i was just pulling your leg

Pull my 3rd next, i also cannot get a cool username style

 

[Tismo]

Pull my 3rd next, i also cannot get a cool username style

PE exercises for length

 

[Biomaxx]

Bump