Guide Aromatase inhibition (2 Viewers)

[Mandy]

birthdefect Hide Mirin FS51 Fram3Let Circadex Biomaxx

Look at this fag nigga how dare you forget to tag me

 

[Mandy]

Bump Son aesthetics acromegalic 9Dino

Look at this fag nigga how dare you forget to tag me

Again

 

[Mandy]

Nice thread though

 

[Biomaxx]

Again

 

[Mandy]

Don’t do that again it pains my heart

 

[Biomaxx]

Don’t do that again it pains my heart

It wont happen again

 

[sensitive sapphire]

It wont happen again

damn nigga you didnt taged me either

 

[Ascension]

Hi
Most of this thread will be assuming your on for your epiphyseal plates

what is aromatase inhibition?
aromatase is the enzyme that converts testosterone to estrogen (specifically e2). A high e2 levels causes:

Higher stress and emotional instability

physical effects (gyno, water retention, worse fat distribution and gain, acne)

Sexual issues ( erectile disfunction, lower sperm count, lower sex drive)

High Blood pressure, hemocrit count, clotting risk, worse insulin sensitivity,worse lipid profile.

Sleep apnea, less quality sleep, less REM, night wakings

And most importantly for most of yall-
E2 is the main drive for epiphyseal plate fusion

taking a aromatase inhibitor either deactivates or kills that enzyme (depending on which one you take )

————————————————————

E2 levels and controlling them

​

Typical Estradiol Ranges by Tanner Stage

-----------------
Artificial intelligence generated and personally estimated, not reliable dyor​

Stage II (Early Puberty): 10 - 24 pg/mL
Stage III (Mid-Puberty): 10 – 35 pg/mL
Stage IV (Late Puberty): 25 – 45 pg/mL
Stage V (Adult): 30-?? pg/mL

-------------------
Low e2 levels are just as bad as high levels

Aromatase inhibitors where originally invented to mitigate breast cancer. So when you go searching up doses and protocol be careful

You want no more than a 20% decrease in e2

Which would be estimated response at these doses of the big 3

Letrozole
0.25mg every 3-4 days
0.5mg weekly

View attachment 32189
Anastrozole
0.25mg every 3-4 days
0.5mg twice weekly

View attachment 32188

Aromasin (what i take)
12.5mg every 3-4 days
6.25mg every other day

View attachment 32187

——————————————————

going over the three

Reversible- The ai binds to the enzyme and "de-activates" it. Upon discontinuing. The ai unbinds and unassociates , this causes an e2 "surge" , where the
Androgen load awaiting aromatization interacts.

Irreversible- the ai binds to the enzyme and kills it. This is why its called a suicidal inhibitor. Upon Discontinuing, the aromatase slowly rebuilds back up to normal levels.


Letrozole-
View attachment 32211
Letrozole is a reversible aromatase inhibitor, the most potent out of the three. Letz causes a quick , harsh drop in e2.

Letz carries harsher sides than others (although still small), because of its harsh qualities and cross interaction with other hormones, harsh on lipids.

Letz also lowers cortisol, does not directly damage the brain contrary to popular belief and obviously causes high overall test levels (20-30%).


Anastrozole-
View attachment 32212
Anastrozole is a reversible ai, in the middle of the three in terms of potentcy, ext.

Relatively low/no sides, mainly due to its low cross interaction.

Anastrozole only lowers aromatase, no effect on cortisol, brain, cns, ext.

aromasin-
View attachment 32213
imo aromasin is the best ai

It is irreversible, a slow,controlled drop and slow, controlled rise after discontinuing.

aromasin also binds to the androgen receptor at a 5% dht and is gentle on lipids.

Although, its steroid structure can slightly increase cholesterol

-AI alone without sufficient compounds = low E2 + insufficient bone growth . The problem isn't the low E2, it's low E2 without IGF-1/androgen signaling.

Thats all I got


​

i offer 1:1 coaching
much luv bhais

Until next time
biomaxx

Nice

 

[sensitive sapphire]

Nice

what is gck?its like the 100th time ive seen it

 

[Ascension]

what is gck?its like the 100th time ive seen it

Goy cux klan

 

[Biomaxx]

damn nigga you didnt taged me either

I was honestly going to, then i thought u already replied but then I went to look and got distracted

 

[TheCoolDude2000]

Good thread bio

 

[Biomaxx]

VelocityAnt Thank you bby

 

[Biomaxx]

Hi
Most of this thread will be assuming your on for your epiphyseal plates

what is aromatase inhibition?
aromatase is the enzyme that converts testosterone to estrogen (specifically e2). A high e2 levels causes:

Higher stress and emotional instability

physical effects (gyno, water retention, worse fat distribution and gain, acne)

Sexual issues ( erectile disfunction, lower sperm count, lower sex drive)

High Blood pressure, hemocrit count, clotting risk, worse insulin sensitivity,worse lipid profile.

Sleep apnea, less quality sleep, less REM, night wakings

And most importantly for most of yall-
E2 is the main drive for epiphyseal plate fusion

taking a aromatase inhibitor either deactivates or kills that enzyme (depending on which one you take )

————————————————————

E2 levels and controlling them

​

Typical Estradiol Ranges by Tanner Stage

-----------------
Artificial intelligence generated and personally estimated, not reliable dyor​

Stage II (Early Puberty): 10 - 24 pg/mL
Stage III (Mid-Puberty): 10 – 35 pg/mL
Stage IV (Late Puberty): 25 – 45 pg/mL
Stage V (Adult): 30-?? pg/mL

-------------------
Low e2 levels are just as bad as high levels

Aromatase inhibitors where originally invented to mitigate breast cancer. So when you go searching up doses and protocol be careful

You want no more than a 20% decrease in e2

Which would be estimated response at these doses of the big 3

Letrozole
0.25mg every 3-4 days
0.5mg weekly

View attachment 32189
Anastrozole
0.25mg every 3-4 days
0.5mg twice weekly

View attachment 32188

Aromasin (what i take)
12.5mg every 3-4 days
6.25mg every other day

View attachment 32187

——————————————————

going over the three

Reversible- The ai binds to the enzyme and "de-activates" it. Upon discontinuing. The ai unbinds and unassociates , this causes an e2 "surge" , where the
Androgen load awaiting aromatization interacts.

Irreversible- the ai binds to the enzyme and kills it. This is why its called a suicidal inhibitor. Upon Discontinuing, the aromatase slowly rebuilds back up to normal levels.


Letrozole-
View attachment 32211
Letrozole is a reversible aromatase inhibitor, the most potent out of the three. Letz causes a quick , harsh drop in e2.

Letz carries harsher sides than others (although still small), because of its harsh qualities and cross interaction with other hormones, harsh on lipids.

Letz also lowers cortisol, does not directly damage the brain contrary to popular belief and obviously causes high overall test levels (20-30%).


Anastrozole-
View attachment 32212
Anastrozole is a reversible ai, in the middle of the three in terms of potentcy, ext.

Relatively low/no sides, mainly due to its low cross interaction.

Anastrozole only lowers aromatase, no effect on cortisol, brain, cns, ext.

aromasin-
View attachment 32213
imo aromasin is the best ai

It is irreversible, a slow,controlled drop and slow, controlled rise after discontinuing.

aromasin also binds to the androgen receptor at a 5% dht and is gentle on lipids.

Although, its steroid structure can slightly increase cholesterol

-AI alone without sufficient compounds = low E2 + insufficient bone growth . The problem isn't the low E2, it's low E2 without IGF-1/androgen signaling.

Thats all I got


​

i offer 1:1 coaching
much luv bhais

Until next time
biomaxx

Bump, this took me like 2 hrs

 

[acromegalic]

Hi
Most of this thread will be assuming your on for your epiphyseal plates

what is aromatase inhibition?
aromatase is the enzyme that converts testosterone to estrogen (specifically e2). A high e2 levels causes:

Higher stress and emotional instability

physical effects (gyno, water retention, worse fat distribution and gain, acne)

Sexual issues ( erectile disfunction, lower sperm count, lower sex drive)

High Blood pressure, hemocrit count, clotting risk, worse insulin sensitivity,worse lipid profile.

Sleep apnea, less quality sleep, less REM, night wakings

And most importantly for most of yall-
E2 is the main drive for epiphyseal plate fusion

taking a aromatase inhibitor either deactivates or kills that enzyme (depending on which one you take )

————————————————————

E2 levels and controlling them

​

Typical Estradiol Ranges by Tanner Stage

-----------------
Artificial intelligence generated and personally estimated, not reliable dyor​

Stage II (Early Puberty): 10 - 24 pg/mL
Stage III (Mid-Puberty): 10 – 35 pg/mL
Stage IV (Late Puberty): 25 – 45 pg/mL
Stage V (Adult): 30-?? pg/mL

-------------------
Low e2 levels are just as bad as high levels

Aromatase inhibitors where originally invented to mitigate breast cancer. So when you go searching up doses and protocol be careful

You want no more than a 20% decrease in e2

Which would be estimated response at these doses of the big 3

Letrozole
0.25mg every 3-4 days
0.5mg weekly

View attachment 32189
Anastrozole
0.25mg every 3-4 days
0.5mg twice weekly

View attachment 32188

Aromasin (what i take)
12.5mg every 3-4 days
6.25mg every other day

View attachment 32187

——————————————————

going over the three

Reversible- The ai binds to the enzyme and "de-activates" it. Upon discontinuing. The ai unbinds and unassociates , this causes an e2 "surge" , where the
Androgen load awaiting aromatization interacts.

Irreversible- the ai binds to the enzyme and kills it. This is why its called a suicidal inhibitor. Upon Discontinuing, the aromatase slowly rebuilds back up to normal levels.


Letrozole-
View attachment 32211
Letrozole is a reversible aromatase inhibitor, the most potent out of the three. Letz causes a quick , harsh drop in e2.

Letz carries harsher sides than others (although still small), because of its harsh qualities and cross interaction with other hormones, harsh on lipids.

Letz also lowers cortisol, does not directly damage the brain contrary to popular belief and obviously causes high overall test levels (20-30%).


Anastrozole-
View attachment 32212
Anastrozole is a reversible ai, in the middle of the three in terms of potentcy, ext.

Relatively low/no sides, mainly due to its low cross interaction.

Anastrozole only lowers aromatase, no effect on cortisol, brain, cns, ext.

aromasin-
View attachment 32213
imo aromasin is the best ai

It is irreversible, a slow,controlled drop and slow, controlled rise after discontinuing.

aromasin also binds to the androgen receptor at a 5% dht and is gentle on lipids.

Although, its steroid structure can slightly increase cholesterol

-AI alone without sufficient compounds = low E2 + insufficient bone growth . The problem isn't the low E2, it's low E2 without IGF-1/androgen signaling.

Thats all I got


​

i offer 1:1 coaching
much luv bhais

Until next time
biomaxx

great thread, includes pretty much everything u gotta know. mirin