made a thread about this a while back but didnt get any answer how much is the impact of smoking/vaping on hight and how can i minimize it
first of all im 68 kg im not fat nigga im skinnyfat and i didnt ask is there an impact i asked how bad is it and what i cant do to minimizestop smoking fatass end of the topic
"If i eat poison will it decrease my height"
ahh question
so if i do 2x a than the maximum is it possible that the effect whould be neutralized or atleast less
No-ones corrected you, and this is your second thread saying "Hight". It's "Height" fyi. Or you're just drunk/high? not even ESL misspells "on" brah
third time bieng drunk and it already turend me into a dumbass
Nicotine = lower cortisol = more GH.
If anyone cares to correct me, you're wrong and a faggot.
Smoking makes me feel like a 1800s cowboy in wild west also (Especially since i smoke unfiltered like a man)
Son the booze will affect your growth not the pack
How it feels like smoking a camel on a hottest day of the summer
Everyone needs to quit alcohol, disgusting poison. I can't touch the stuff without vomiting anymore.
Keep drinking down to 10 times a year max.
I’m repulsed by the slightest hint of the smell for a week after being drunk one time. Also ye generally I limited alcohol a lot when I realized it tanks your LH for 3-5 days.
For me it's like 1-3 months lmao. And i just don't like being drunk tbh, i always get really bad heartburn and feel like shit the next day. I prefer weed but that i also keep to like 15 times a year maximum. Yet I've only smoked like 7 times this year. Rule of thumb is: if you're not getting ZONKED from 0.5 g you're smoking too much, too regularly.
Man I love weed but I have the tendency to rather fall asleep randomly even if it’s sativa. I also have the tendency to just be high 24/7 from the moment I wake up till night for multiple days whenever I get my hands on. I’m getting some today,hopefully I can discipline myself.
they are not realy friends i hang out with them so i could slay i slayd 3 times in the past 2 month bcuz of them so somtimes i have to endure some shit
Good luck man, discipline is important with drugs.
This also reminded me of that weed hang over, idk if anyone else experiences it but im literally high when i wake up if i smoke weed
.None of my friends experience it which is weird, i basically get a whole extra day out of a joint.
I just wake up extremely sluggish after falling asleep high,thats the reason why I have a urge to blaze one up right away once I open my eyes.Good luck man, discipline is important with drugs.
This also reminded me of that weed hang over, idk if anyone else experiences it but im literally high when i wake up if i smoke weed
None of my friends experience it which is weird, i basically get a whole extra day out of a joint.
the entire process of linear growth (via chondrocyte proliferation, chondrocyte hypertrophy, matrix mineralization, osteoblastic replacement) gets interfered by smoking.
nicotine suppresses the GH-IGF1 axis.
in normal physiology, this would be the case:
hypo -> ghrh
pituitary -> pulsatile gh secretion
liver -> igf1
igf1 -> chondrocyte div in growth plates
what nicotine does:
activates alpha4beta2 nictinic acetylcholine receptor at CNS
increase dopamine and cortisol
blunts nocturnal gh pulses
reduces hepatic igf1 synthesis
Nicotine also causes chronic hypoxia at growth plate level
bcz growth plates are avascular so they rely ENTIRELY on O2 and nutrients diffusion from surrounding capillaries
what smoking introduces:
CO (carbon monoxide) -> binds Hb with 200x (iirc) affinity of O2
nicotine -> vasoconstriction (bcz of sympathetic activation)
endothelial dysfunction -> less nitric oxide available
THAT OVERALL creates functional hypoxia in the growth plates
hypoxia inhibits chondrocytic hypertrophy, accelerates premature closure of plates, activates hypoxia inducible stress pathways instead of growth pathways like in normal niggas
also cortisol is raised
cortisol inhibits collagen type II synthesis
there's a toxicity to griwth plate chondrocytes as well because tobacco smoke contains:
polycyclic aromatic hydrocarbons
cadmium
reactive oxygen species
they induce oxidative DNA damage in chondrocytes, increase apoptosis, reduce extracellular matrix production, activate inflammatory NF-kB signalling (couldn't find the symbol)
then nicotine also alters DNA methylation patterns, histone acetylation, microRNA expression related to growth and they reduce responsiveness to gh and igf1
nicotine suppresses the GH-IGF1 axis.
in normal physiology, this would be the case:
hypo -> ghrh
pituitary -> pulsatile gh secretion
liver -> igf1
igf1 -> chondrocyte div in growth plates
what nicotine does:
activates alpha4beta2 nictinic acetylcholine receptor at CNS
increase dopamine and cortisol
blunts nocturnal gh pulses
reduces hepatic igf1 synthesis
Nicotine also causes chronic hypoxia at growth plate level
bcz growth plates are avascular so they rely ENTIRELY on O2 and nutrients diffusion from surrounding capillaries
what smoking introduces:
CO (carbon monoxide) -> binds Hb with 200x (iirc) affinity of O2
nicotine -> vasoconstriction (bcz of sympathetic activation)
endothelial dysfunction -> less nitric oxide available
THAT OVERALL creates functional hypoxia in the growth plates
hypoxia inhibits chondrocytic hypertrophy, accelerates premature closure of plates, activates hypoxia inducible stress pathways instead of growth pathways like in normal niggas
also cortisol is raised
cortisol inhibits collagen type II synthesis
there's a toxicity to griwth plate chondrocytes as well because tobacco smoke contains:
polycyclic aromatic hydrocarbons
cadmium
reactive oxygen species
they induce oxidative DNA damage in chondrocytes, increase apoptosis, reduce extracellular matrix production, activate inflammatory NF-kB signalling (couldn't find the symbol)
then nicotine also alters DNA methylation patterns, histone acetylation, microRNA expression related to growth and they reduce responsiveness to gh and igf1
Facts bro nicotine made me 5 inches taller in 2 days so he must be spreading some bullshit
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