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Feeling cute , might write intro later
THREAD SUGGESTION BY
Circadex ty papi
-Sure! I can write a couple paragraphs about isotretinoins non acne effects! -
LÉ NOS
The nose isn't primarily composed of cartilage (visually), it's skin thickness plus sebaceous gland density laid over cartilage. Isotretinoin dramatically shrinks sebaceous glands and suppresses sebum production long term. In areas where this glandular density is high (nose, nasolabial folds, central face), this reduces volume and surface oiliness, making contours appear sharper. The cartilage doesn't change; the overlying soft tissue does. This is why the effect is more pronounced in people with oily skin or thicker sebaceous skin to begin with.
LIPS
What it does is modify keratinization and barrier function. The vermilion becomes drier, yes, but also thinner in the stratum corneum, which can make vascularity more visible and borders appear sharper. On some faces this reads as slightly fuller or more defined lips, especially when surrounding skin loses oil and thickness.
COLLAGEN (insert collagen emoji)
Isotretinoin downregulates matrix metalloproteinases )the enzymes that destroy collagen) and influence fibroblast behavior. This can improve collagen organization and slow its degradation but wont massively increase its total content. So it doesn't exactly build nee collagen but control deteriorating how the existing fibers are laid out. This explains why some people notice smoother skin texture and reduced pore appearance even after stopping the drug.
Uhhhh conclusion bc icba
The non-acne effects of isotretinoin are not side perks but rather downstream consequences of the suppression of the sebaceous phenotype and/or the promotion of retinoid-driven cellular differentiation.
Short thread ik but you should kill yourself
Wow! What a great thread !
Im bouttaaaa buuuummmmppp
THREAD SUGGESTION BY
Circadex ty papi-Sure! I can write a couple paragraphs about isotretinoins non acne effects! -
LÉ NOS
The nose isn't primarily composed of cartilage (visually), it's skin thickness plus sebaceous gland density laid over cartilage. Isotretinoin dramatically shrinks sebaceous glands and suppresses sebum production long term. In areas where this glandular density is high (nose, nasolabial folds, central face), this reduces volume and surface oiliness, making contours appear sharper. The cartilage doesn't change; the overlying soft tissue does. This is why the effect is more pronounced in people with oily skin or thicker sebaceous skin to begin with.
LIPS
What it does is modify keratinization and barrier function. The vermilion becomes drier, yes, but also thinner in the stratum corneum, which can make vascularity more visible and borders appear sharper. On some faces this reads as slightly fuller or more defined lips, especially when surrounding skin loses oil and thickness.
COLLAGEN (insert collagen emoji)
Isotretinoin downregulates matrix metalloproteinases )the enzymes that destroy collagen) and influence fibroblast behavior. This can improve collagen organization and slow its degradation but wont massively increase its total content. So it doesn't exactly build nee collagen but control deteriorating how the existing fibers are laid out. This explains why some people notice smoother skin texture and reduced pore appearance even after stopping the drug.
Uhhhh conclusion bc icba
The non-acne effects of isotretinoin are not side perks but rather downstream consequences of the suppression of the sebaceous phenotype and/or the promotion of retinoid-driven cellular differentiation.
Short thread ik but you should kill yourself
Wow! What a great thread !
Im bouttaaaa buuuummmmppp
